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About This Podcast
Haley Berkoe asks some of the biggest names in bitcoin and Silicon Valley 21 questions in 21 minutes, from the personalities you know and love to tech’s unsung heroes. A new episode drops when someone stops by Presidio Bitcoin. Reach out if you are or will be in the area and are interested in being on the show. presidiobitcoin.substack.com
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Recent Episodes
21 in 21: Calle on Cashu, Clawi, and AI Agents
On this episode of 21 in 21, Calle discusses his work on Cashu, Bitchat, and Clawi. He explores how AI agents could use bitcoin-native payments and why privacy-preserving infrastructure matters in an…
21 in 21: Linn Bieske on Hack-Nation and Building Global AI Communities
Linn Bieske, Co-Lead of the AI & Technology Track at the MIT Club of Northern California (CNC), AI Product Manager, and Co-Founder of Hack-Nation, joins Haley Berkoe on 21 in 21. They discuss the…
21 in 21: Rainey Reitman on Transaction Denied and Financial Censorship
Rainey Reitman joins 21 in 21 for a conversation on financial censorship, free speech, and her new book, Transaction Denied: Big Finance’s Power to Punish Speech. Rainey co-founded Freedom of the…
21 in 21: Michael Saylor on Bitcoin, AI, and Advice for Builders
Michael Saylor joined Haley Berkoe on 21 in 21 for a rapid-fire conversation on bitcoin, AI, and what’s coming next. He shares what’s top of mind for 2026, why he sees this year as a major turning…
21 in 21: Andi Pitt on Bitcoin Venture, AI, and Cognitive Sovereignty
Andi Pitt of Ego Death Capital joined me on 21 in 21 to talk about the rise of new startups in the bitcoin ecosystem, how the funding landscape has changed, and the growing intersection of bitcoin…
21 in 21: Mark Suman on Privacy-First AI
Mark Suman, co-founder and CEO of Maple AI, a privacy-first AI chat platform known as “the Signal of AI,” joins Haley Berkoe on 21 in 21. Mark explains how Maple AI uses secure enclaves to deliver a…
21 in 21: David Gumberg on the Chaincode ₿OSS Challenge and Becoming a Bitcoin Core Contributor
Haley Berkoe sits down with David Gumberg, a Bitcoin Core contributor at Localhost, a bitcoin-focused research center in the Bay Area. David shares how he got into bitcoin, what pushed him from…
21 in 21: Rod Roudi
In this episode of 21 in 21, Haley sits down with Rod Roudi, co-founder of Bitcoin Park in Nashville and Austin. Rod breaks down how Bitcoin Park began, why in-person energy fuels strong communities,…
21 in 21: Joe Carlo on How Bitcoin Changed Pink Owl Coffee Forever
Haley Berkoe sits down with Joe Carlo, co-owner of Pink Owl Coffee, a café that began in San Rafael, California, and has since expanded to three locations across the Bay Area. Pink Owl is one of the…
21 in 21: Kyle Olney
Kyle Olney joins Haley Berkoe to talk about defending bitcoin’s foundational freedoms. A longtime Silicon Valley product leader turned bitcoin advocate, Kyle helped launch Save Our Wallets, a…
21 in 21: Nick Slaney
In this episode of 21 in 21, Nick Slaney joins Haley Berkoe during Presidio Bitcoin Design Week. Nick is the founder of Money Dev Kit, a new startup building tools that make it easy for developers to…
21 in 21: Erik Cativo
During Bitcoin Design Week at Presidio Bitcoin, product designer and HRF grantee Erik Cativo joined the show to talk about designing the future of money. We get into his experiments with ecash and…
21 in 21: Kyle Fletcher
Haley Berkoe is joined by Kyle Fletcher, Principal Design Director at Block, to explore the intersection of bitcoin, design, and culture. They discuss why artists and designers play a critical role…
21 in 21: Christoph Ono
In this episode of 21 in 21, Haley is joined by Christoph Ono, co-founder of the Bitcoin Design Foundation and longtime contributor to the Bitcoin Design Community. They talk about Bitcoin Design…
21 in 21: Conor Okus
In this episode, Haley Berkoe interviews Conor Okus, a Product Manager at Spiral. Conor shares his journey from playing football to becoming a grantee at Spiral and now managing the grant program. He…
21 in 21: Mogashni Naidoo
Haley Berkoe sits down with Mogashni “Mo” Naidoo — UX researcher, designer, and co-founder of the Bitcoin Design Foundation. Mo shares her path into bitcoin design, why developers and designers need…
21 in 21: Matthew Pines
Haley Berkoe talks with Matthew Pines, Executive Director of the Bitcoin Policy Institute, about bitcoin’s growing role in U.S. policy. They cover building a bitcoin community in DC, how policymakers…
21 in 21: Tadge Dryja
Haley Berkoe met with Tadge Dryja, a bitcoin developer, researcher, and co-creator of the Lightning Network. They discussed the importance of preparing for potential threats from quantum computing…
21 in 21: Jameson Lopp
In this episode, Haley Berkoe chats with Jameson Lopp, longtime bitcoiner, cypherpunk, and Chief Security Officer at Casa, to explore the long-term threats and opportunities facing bitcoin. He…
21 in 21: Alex Pruden
This episode features Alex Pruden, the Chairman of Aleo and the CEO of Project Eleven, an applied R&D lab focused on the intersection of quantum computing and cryptography. In this conversation…
Frequently Asked Questions
21 in 21 has published 35 episodes since March 2025, covering topics in Business, Education.
21 in 21 is currently highly active with new episodes every 2 weeks. Average episode length is 23m.
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