Absolute Gene-ius
Jordan Ruggieri, Lisa Crawford
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Explore Statistics
Recent Episodes
S4E6 Finding the cheat codes to cell identity
In this episode, Fiona Connolly, former Platform Innovation and Automation Scientist at bit.bio, explains how deterministic programming replaces the traditional “pinball machine” model of stem cell…
S4E5 Science happens, and so do mistakes
Science doesn’t just advance through breakthroughs, it advances through mistakes. This Science Snapshot episode embraces a universal truth of research: if you haven’t messed something up in the lab,…
S4E4 Almost a virus – how AAV powers modern gene therapy
Viruses are not always something to fear; they can also be tools to heal. This episode looks into this positive side of viral biology.Dr. Dan Mitchell, Senior Director of Analytical Development and…
S4E3 How sequencing and PCR work together in oncology research
In this episode of Absolute Gene-ius, the hosts dive into the evolving world of precision oncology, where detecting rare molecular signals can make all the difference. Dr. Kathie Sollweck brings deep…
S4E2 When PCR gets dirty - tackling PCR inhibitors
PCR inhibitors are everywhere and they can definitely mess with your data. From muddy lake water to complex viral vector preparations, inhibition is a reality that can’t be ignored.In this inaugural…
S4E1 Tracking grape pathogens from air to vine
What do vineyards, airborne spores, and digital PCR have in common? Turns out – quite a lot. This episode kicks off Season 4 by going green with plant pathology and molecular diagnostics. Lexi Heger,…
S4 Season 4 – new voices, new discoveries
We’re back and better than ever. Season 4 of Absolute Gene-ius is officially here, and this teaser gives you a front-row seat to what’s coming. From scientific puns to sneak peeks of the upcoming…
S3E6 Digital PCR and the fight against HIV-2 and superbugs
HIV, superbugs, and standards—oh my! In this episode of Absolute Gene-ius, we explore the frontier of infectious disease research with Dr. Jesús Mingorance, researcher at Hospital Universitario La…
S3E5 Biomarkers in motion ― detecting Alzheimer's through saliva
Can you detect Alzheimer’s with a spit sample? That’s the question driving Arianna Arbona’s exciting research at Universidad Pablo de Olavide in Sevilla, Spain. In this episode of Absolute Gene-ius,…
S3E4 Python problems – digital PCR takes on the Everglades
This episode of Absolute Gene-ius slithers into the surprising science of invasive species monitoring with Dr. Brian Bahder. A childhood love of bugs led Brian to a dynamic career in entomology and…
S3E3 Life finds a way – copy number variation and drug metabolism
Ever thought about why medications work differently for different people? In this episode of Absolute Gene-ius, we explore the exciting field of pharmacogenomics with Wendy Wang, pharmacogenetic…
S3E2 Unlocking cancer’s genetic secrets with digital PCR
Scientific discovery happens in the lab—but it starts with curiosity and determination. In this episode of Absolute Gene-ius, we welcome Valeria Rangel, a PhD candidate at the University of…
S3E1 CRISPR, dPCR, and pigs – a cut above the rest
In this episode of Absolute Gene-ius, Dr. C. Dustin Rubinstein takes us inside the world of advanced genome editing, where cutting-edge tools like CRISPR and digital PCR are helping shape the future…
S2E13 Season two amplified – reflections and takeaways
Season 2 of Absolute Gene-ius comes to a close with a look back at the topics and inspiring conversations that have defined the series. From exploring innovative uses of digital PCR to uncovering its…
S2E12 The Poisson perspective – counting out false positives
The statistics of Poisson distributions can seem complex at first but are simpler than you think, which is important to know given their relevance to digital PCR. In short, they dictate the…
S2E11 Somatic mosaic loss of sex chromosomes and kidney disease
Same may think of the pathologist’s toolbox as only the microscope and their eyes, but in reality today’s pathologists are using more and more molecular methods like NGS and PCR in additional to…
S2E10 Automating accuracy – an insider’s view
Modern science, especially in the genetic and molecular biology spaces, generate vast amounts of data, and require vast amounts of data to be generated for thorough analysis. For example, finding a…
S2E9 Helping democratize access and use of mRNA technology
The potential of mRNA medicines was postulated for years, but it took the COVID pandemic and emergency use authorizations for that potential to be demonstrated. By now, most of us have received at…
S2E8 Now that’s what I call a high-quality viral vector
Viral vectors are a cornerstone of gene therapy and many employ experts in the viral vector services space to help design and produce their specialty vectors. These service providers are experts at…
S2E7 Ch-ch-ch-ch-changes
When you have a good thing going you often want it to last forever, but we know that can never happen. Life and the world around us are fluid, dynamic, and we’re always finding the balance of…
Frequently Asked Questions
Absolute Gene-ius has published 38 episodes since April 2023, covering topics in Chemistry, Life Sciences.
Absolute Gene-ius is currently highly active with new episodes monthly. Average episode length is 34m.
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