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Beyond the Headlines: PMDD and Antihistamines, Real-Time FDA Study Monitoring Using Al, and More!
In this Beyond the Headlines episode, we examine the FDA's push for real-time clinical trial data, an executive order making psychedelic research a federal priority, advances in CAR T-cell therapy…
The COPD Gap: Diagnosis, Treatment, and Access
COPD is the third leading cause of death worldwide. Yet the disease remains underdiagnosed and underfunded. Host Emily O'Brien and pulmonologist Chris Mosher discuss stigma, funding disparities,…
Hard Habits: What Kidney Stones Teach Us About Behavior Change
Why is it so hard to change our behavior, even when we know what we should be doing? Host Emily O'Brien sits down with urologist and DCRI faculty member Dr. Chuck Scales to discuss the science of…
Closing the Gap in Cardiac Arrest Survival: Why Bystanders Matter
During a cardiac event, every minute without CPR reduces survival chances by 10%. In this episode, DCRI's Tyler Cope discusses a coordinated effort to train nearly 20,000 people across North Carolina…
From Research to Relief: Raising the Standard in Back Pain Treatment
Nearly 40% of Americans have experienced back pain in the past three months, yet treatment hasn't kept pace with the science. Host Emily O'Brien talks with DCRI researcher Steven George about…
All About Allergies: The Evolution of Care & Evidence with Dr. Zach Rubin
Double-board-certified pediatrician and allergist/immunologist Zach Rubin joins Manesh Patel for an evidence-based discussion on allergy science. The conversation dives into the differences between…
From Innovation to Implementation: AI in Action
Guests Michael Pencina and Suresh Balu join the Beyond the Endpoint hosts to explore the impact of AI in healthcare. They discuss the role of AI-powered tools in research, clinical care, and…
Beyond the Headlines Series: Looking back at 2025 headlines, Dementia & Vaccines, and Cannabis Research
Kick off 2026 with hosts Manesh Patel and Emily O'Brien as they evaluate last year's most discussed health stories and wellness trends, cannabis reclassification, and a shingles vaccine-dementia…
Behind the Voices: Get to Know Emily & Manesh
Hosts Manesh Patel and Emily O'Brien share their amusing and inspiring personal and professional trajectories, exploring how mentors shaped their paths in clinical research, why asking unconventional…
From Provider to Patient: A Dual Perspective on Colorectal Cancer
Hosts Emily O’Brien and Manesh Patel sit down with Dr. Ajay Kohli and Dr. Julius Wilder for a dual-perspective conversation on colorectal cancer, where they discuss personal experiences, the…
Beyond the Headlines: Recap of the 2025 AHA Scientific Sessions
Recorded at the 2025 American Heart Association Scientific Sessions, hosts Manesh Patel and Emily O'Brien discuss late-breaking cardiovascular research, including gene-editing therapy for…
Connecting the Dots: The Broader Applications of GLP-1s and Where We’re Headed Next
Endocrinologist Jennifer Green discusses how GLP-1 drugs, like Ozempic, evolved from diabetes tools to potential treatments for addiction and heart disease, in this final installment of the obesity…
Obesity, GLP-1s, and the Evidence: What the Data Tells Us
In this second episode of our obesity series, preventive cardiologist Neha Pagidipati sheds light on the discovery, impact, and uses of GLP-1s, like Ozempic and Mounjaro. Learn about the impact these…
It's Not Just the Scale: Supporting Sustainable Change in Obesity Treatment
In the first of a three-part series on obesity and GLP-1 medications, our guest Jennifer Norris shares the evolving landscape of obesity treatment. The conversation addresses common misconceptions…
Beyond the Headlines: Funding Research, Vaccines, Sleep Health, and AI in Healthcare
The "Beyond the Headlines" series returns with summer healthcare and research news. Hosts Manesh Patel and Emily O'Brien discuss misconceptions about research funding, a Danish study on vaccine…
Understanding Autism: Insights from Research and Practice
Ushering in the second season of Beyond the Endpoint, Lauren Franz, MBChB, MPH, interim director of the Duke Center for Autism and Brain Development, joins Manesh Patel and Emily O'Brien for an…
Playing to Advance Care: A Championship Mindset in Clinical Research
What do championship sports teams and successful research institutions have in common? In the season finale of Beyond the Endpoint, Dr. Adrian Hernandez joins hosts Manesh Patel and Emily O’Brien…
Beyond the Headlines: Protein myths. Anti-aging hype. Autism research. A new diabetes drug?
In this new episode of the Beyond the Endpoint series, “Beyond the Headlines,” hosts Emily O’Brien and Manesh Patel break down what’s you should know about these trending medical topics. From hype…
Stepping Up: From Curiosity to Confidence — What to Know Before You Join a Trial
Why do people volunteer for clinical trials — and what should they know before doing so? In this episode of Beyond The Endpoint, we explore common questions, reasons, and myths about clinical trial…
Stepping Up: Why Participate in Clinical Research?
In this episode, cancer survivor Katie Ortman-Doble opens up about her journey through clinical research and why she chose to participate. Hosts Emily O’Brien and Manesh Patel, joined by Jenny Cook,…
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Beyond the Endpoint has published 48 episodes since April 2017, covering topics in Science.
Beyond the Endpoint is currently active with new episodes every 2 weeks. Average episode length is 25m.
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