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Recent Episodes
The Killer Gene That FOUGHT BACK
In this deep dive, we break down the journey of the PIM Kinase target. We explore the complex PIM1 molecular mechanism, examine why first-generation pan-PIM inhibitors like AZD-1208 faced safety…
The Mysterious Gene Behind Blood Clots
Disclaimer: This video is for educational purposes only and should not be used for medical diagnosis or treatment decisions. Always consult with healthcare professionals for medical advice.In this…
KGWAS: novel genetics discovery enabled by massive functional genomics knowledge graph
KGWAS is a novel geometric deep learning method that leverages a massive functional knowledge graph across variants and genes to significantly improve detection power in small-cohort GWASs. Thank…
Low overlap of transcription factor DNA binding and regulatory targets
This podcast was made possible by CIUT-FM 89.5, University of Toronto Community Radio. For more content visit https://ciut.fm/Link to the paper:https://www.nature.com/articles/s41586-025-08916-0Join…
K562 cell Masterclass | Dr. Tom Karagiannis
This podcast was made possible by CIUT-FM 89.5, University of Toronto Community Radio. For more content, visit https://ciut.fm/Join us for this comprehensive masterclass episode as we explore the…
Diabetes, GWAS, Biobanks | Dr. Andrew Paterson
Dr. Andrew Paterson is a Senior Scientist in Genetics & Genome Biology at SickKids and a Professor at the Dalla Lana School of Public Health, University of Toronto. His work focuses on uncovering…
Nextflow, nf-core pipelines, MultiQC
If you’ve ever analyzed sequencing data, chances are you’ve used tools developed by Phil Ewels—whether you knew it or not. He’s the creator of MultiQC, a key developer behind Nextflow and nf-core,…
S2E1 How Genomics Shapes Public Health in Bangladesh | Dr. Senjuti Saha
Welcome to today's episode. I'm excited to introduce our guest, Dr. Senjuti Saha, the Deputy Executive Director of the Child Health Research Foundation in Bangladesh. Dr. Saha is a trailblazer in…
S1E6 - Ethical Crossroads in Genomics | Dr. Yann Joly
Professor Joly is an internationally acclaimed figure in health law, intellectual property, and bioethics, leaving an enduring impact on the ethical landscape of modern medicine. With pivotal roles…
S1E5 - Human Pangenome Reference | Cristian Groza
In this episode, we delve into the intricate world of the human pangenome with Cristian Groza, a Ph.D. student specializing in bioinformatics from Bourque lab at McGill University. A Draft Human…
S1E4 - Cholesterol and Parkinson's: A Genetic Dance of Sex Differences | Dr. Sarah Gagliano Taliun
Episode Notes Dr. Sarah Gagliano Taliun is a researcher affiliated with the Montréal Heart Institute and the Université de Montréal. She specializes in neurogenetics, complex traits, and genomics.…
S1E3 - Identifying GWAS target genes with STING-seq | Dr. John A. Morris
Episode Notes Dr. John A. Morris is a Postdoctoral Scientist at the New York Genome Center, supported by a NHGRI K99 Fellowship. His work aims to understand common human genetic variation through…
S1E2 - Genome-wide association studies (GWAS) | Dr. Daniel Taliun
Episode Notes Dr. Daniel Taliun is a Human Genetics Assistant Professor at McGill University. His research interests are in developing computational algorithms and software tools for analyzing…
S1E1 - Genome Editing and CRISPR/Cas9 | Dr. Raquel Cuella Martin
Dr. Raquel Cuella Martin joined the Department of Human Genetics and the Canada Excellence Research Chair in Genomic Medicine as an assistant professor in August 2022. Dr. Martin's current research…
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Double-stranded has published 14 episodes since March 2023, covering topics in Science.
Double-stranded is currently sporadic with new episodes every 2 weeks. Average episode length is 1h 6m.
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