Dr RR Baliga's "Got Knowledge Doc" Podkast
Dr RR Baliga, MD, MBA
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Great Doctors Series: Herophilus and the Birth of Scientific Anatomy ⚕️🌍
⚕️🧠 Before modern anatomy labs, there was Herophilus (335–280 BCE)—the physician often called the Father of Anatomy. Working in Alexandria, he became the first known scientist to systematically…
🫀 The Heart on Fire: New Frontiers in Cardiovascular Inflammation
🫀🔥 Is cholesterol the whole story behind heart disease? Increasingly, the answer appears to be no. A fascinating Nature Medicine review explores how cardiovascular inflammation is emerging as a major…
🫁 Predict, Prevent, Protect: Plasma Signals That Foretell Lung Cancer Years Ahead
🫁🔬 Can a simple blood test identify people at risk for lung cancer years before diagnosis? A remarkable new study in Cell describes a 14-protein plasma signature that predicts lung cancer more than…
❤️🩹 Sensitized, Desensitized, Transplanted: CAR-T Opens a New Door in Kidney Transplantation
🧬 Groundbreaking NEJM report! Two highly sensitized kidney transplant candidates (cPRA ~99.995–99.998%) underwent successful transplantation after dual CD19- and BCMA-targeted CAR-T therapy. 🎯 …
💥 Ruptoblasts, Ruptosis & Revelation: The Immune Cells That Explode to Protect
💥 What if an immune cell could defend the body by literally exploding? A fascinating new study in Cell describes "ruptoblasts," a previously unknown cytotoxic cell type in planarian flatworms.…
❤️📱 Pulse. Predict. Prevent: The Smartphone That Knows Your Heart
📱❤️ Can your smartphone become a heart monitor? A landmark Nature study demonstrates that passive heart-rate monitoring using a smartphone's front-facing camera can accurately measure heart rate…
🧠 Heart. Liver. Brain: Alcohol's Impact Across the Lifespan
🍷 How much alcohol is truly safe? A landmark Burden of Proof study published in Nature Health analyzed 843 cohort and case-control studies examining alcohol and 20 major health outcomes. Key…
Great Doctors Series: Bian Que, China's Legendary Healer
🏮⚕️ More than 2,300 years ago, the legendary Chinese physician Bian Que (Qin Yueren) taught a lesson that remains central to medicine today: detect disease early. Known for his four-step diagnostic…
💡 Brain Health, Biomarkers & Breakthroughs: A New Chapter in Alzheimer's Disease?
🧠 Alzheimer's disease remains the leading cause of dementia worldwide, but the field is changing rapidly. New advances in genetics, blood-based biomarkers, amyloid and tau PET imaging, and…
📊 From Trial to Clinic: Which Blood Pressure Drugs Patients Tolerate Best?
🩺💊 Which blood pressure medications do patients tolerate best? A major JAMA network meta-analysis of 716 randomized trials involving 159,362 participants found important differences in adverse…
🧬 Decode. Predict. Transform: The Transcriptomic Secrets of Ageing
🧬 Aging leaves a molecular fingerprint—and we can now read it. A remarkable Nature study analyzed >11,000 transcriptomes across mice, rats, macaques, and humans to identify universal…
🫀 Hidden. Dangerous. Overlooked: Coronary Microvascular Dysfunction
🫀 Coronary microvascular dysfunction is no longer a "hidden" diagnosis. The new FLOW-CMD Registry published in The Lancet demonstrates that coronary microvascular dysfunction frequently coexists…
🫀 Beyond Pumps and Pills: BioVAT and the Future of Heart Failure Therapy
🫀 Fascinating new study in the The New England Journal of Medicine explores "Stem-Cell–Derived Biologic Ventricular Assist Tissue (BioVAT)" for advanced heart failure. Investigators demonstrated that…
💉 One Shot, Lifelong LDL reduction? The Promise of Genomic Cardiology
🧬 Could a single infusion replace decades of lipid-lowering therapy? The new NEJM study on VERVE-102 explores in vivo base editing of PCSK9 using CRISPR-inspired adenine base editing technology. In…
Diocles, The Forgotten Greek Pioneer: Observation. Balance. Wellness ⚖️🩺
⚕️ Long before modern preventive medicine, Diocles of Carystus emphasized something remarkably familiar today: hygiene, exercise, balanced diet, sleep, and daily discipline. A physician of 4th…
Beyond Bariatric Surgery: Retatrutide and the 30% Weight Loss Frontier 🚀
⚖️🚀 RETATRUTIDE may redefine obesity medicine. In the Phase 3 TRIUMPH-1 trial, Lilly's triple agonist (GIP/GLP-1/glucagon) achieved an astonishing 28.3% average weight loss at 80 weeks, with some…
🚑 ICU Lines Under Siege: How EDTA Is Changing Critical Care
🧪 New in JAMA: 4% tetrasodium EDTA significantly reduced ICU catheter complications in a multicenter randomized clinical trial. Among 1,468 critically ill patients, EDTA locking solution lowered…
🌙🧠 Sleep. Sync. Survive: The Oscillatory Brain and Dementia
🌙🧠 Fascinating new insights from Science reveal that sleep is far more than "rest." During non-rapid eye movement sleep, neuromodulators synchronize into ~50-second oscillatory rhythms that…
🧪❤️ Preserved. Processed. Pressured: Food Additives and Heart Disease
🧪❤️ Are preservatives in ultra-processed foods quietly increasing cardiovascular risk? A major analysis from the NutriNet-Santé cohort published in the European Heart Journal followed >112,000…
⚡ Beyond Carbapenems: The Nacubactam Revolution in complicated UTI
🦠 The INTEGRAL-1 trial in The Lancet delivers exciting data for resistant urinary tract infections. Cefepime–nacubactam achieved both noninferiority AND superiority vs imipenem–cilastatin in…
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Dr RR Baliga's "Got Knowledge Doc" Podkast has published 967 episodes since June 2019, covering topics in Education, Natural Sciences.
Dr RR Baliga's "Got Knowledge Doc" Podkast is currently highly active with new episodes daily. Average episode length is 5m.
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