Explain Podcast

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explain.pod

English Natural Sciences Science

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Episodes 28

Avg. Duration 46m

Activity Active

Apple Rating ★ 5.0 (1)

Since Jun 2023

Latest Episode Apr 2026

Publishing Details

Schedule

Monthly

Format

Episodic

Consistency

29%

Hosting

anchor.fm

Contact & Outreach

About This Podcast

The Podcast Explain is for everyone interested in DNA/RNA sequencing or technology in general. As Iuliia doesn't have a solid background in sequencing, she keeps asking "simple" - even silly at times - questions and Daniel gives his best to make us understand.

Explore Statistics

English Podcasts Report Natural Sciences Report Science Report English Natural Sciences Report

Recent Episodes

454.bio

Apr 07, 2026 25m

The open-source DIY Sequencer was here.Update: 454.bio is now dead, but the archives still have it: https://web.archive.org/web/20250723191639/https://454.bio/Their…

Special: other Nanopore Sequencing

Mar 20, 2026 38m

We have the same thing at home!- yes, but in worse, cheaper or bothQitan:https://pmc.ncbi.nlm.nih.gov/articles/PMC8985760/https://www.qitantech.com/The QPinnacle2:…

News: AlphaGenome, Vibecoding

Mar 10, 2026 35m

Artificial Intelligence everywhere, and sometimes its useful.Correction: apparently the Biostar Handbook is not free anymore…

News: PacBio, Illumina, Nanopore...

Feb 20, 2026 24m

When do you get your Illumina sticker for your ONSO? This is the first part of a two-parts news roundup.PacBio…

Array Sequencing

Dec 23, 2025 41m

For when matching and sticking is enough to getLinks:Nice Youtube explainer: https://www.youtube.com/watch?v=NgRfc6atXQ8Another nice one: https://www.youtube.com/watch?v=4bOY2Oh5tEQExplaining this…

Sequencing by Expansion (SBX)

Nov 18, 2025 42m

After 454 now the second try by Roche: Axelios.Preprint: https://www.biorxiv.org/content/10.1101/2025.02.19.639056v1Read here about the PoC:…

News: 23andMe

Oct 02, 2025 21m

This time something…

Special: Sequencing in Immunology

Aug 06, 2025 57m

The science of white blood cells, and much moreChapters:05:30 Immunology how?22:05 22q11.2 deletion syndrome34:30 Scientific collaboration40:00 Data losses50:00 Flip it!53:00 outlook…

E15: Singular Genomics | ATAC-seq

May 28, 2025 46m

Sharing a flowcell, reinventedChapters:- 00:00 usegalaxy.org- 07:55 Singular Genomics start- 21:55 Max Reads- 29:40 DNA Structure / ATAC-seqSetup galaxy on local hardware:…

E14: Ultima Genomics + Element UltraQ

Apr 02, 2025 46m

Spinnin' bases on wafers to do mostly natural SBSChapters:- 00:00 Ultima ePCR with beads- 07:10 Spinning the wafer, nucleotides, no blocking- 14:30 Ultima ppmSeq + Element UltraQ- 25:30 How Element…

E13: Sequencing by Avidity | Element Biosciences + XLEAP

Mar 12, 2025 39m

Because sometimes a jellyfish prevents quenchingChapters:01:00 - XLeap update from Illumina08:00 - Avidites start, splitting the problems13:20 - In-depth comparison to Illumina22:00 - Element…

E12: ONSO | Sequencing by binding

Jan 28, 2025 54m

Now Illuminas IP, previously PacBios, previously OMNIONE...Because only one type of nucleotide is not complicated enoughChapters:01:35 Introducing old problems15:30 More Phred, more better34:40…

Special: Long vs Short reads

Aug 01, 2024 1h 11m

Mixing up long and cheap... soon we need to add "vs mid-reads"Chapters:00:00:00 Intro00:03:30 Florians history00:13:50 Q&A Ressources for Bioinformatics00:27:00 Long-read-tools.org00:35:42 ONT ||…

E11: MGI DNA Nanoball sequencing

Jul 02, 2024 36m

Rolling in circles to make DNA yarnsChapters:00:00 Bioinformatics Upper Crust Tools04:04 STAR05:00 MGI15:00 Daniels first contact20:00 Brief Market Overview22:30 Short read market26:00 DFG High Costs…

S2E1 E10: Genome Mapping

May 27, 2024 48m

Who needs all bases anyway?Chapters:00:00 Phasing08:50 Not Sequencing, really14:00 Bionano Saphyr Chip26:00 Nabsys - going electric29:30 Tools available39:00 QuickGen with Iuliia:…

E9: Single Cell Sequencing

Mar 22, 2024 1h 10m

Chapters:00:00 Gambling15:00 Bubbles30:00 Holes57:30 One more thing1:07:00 Finale1:08:00 Finale of season 1!Eric Chow explaining single cell sequencing:…

Special: PhiX / UMIs / QC

Feb 09, 2024 1h 10m

Getting the most out of MachinesChapters:00:00 PhiX14:30 low complexity19:30 UMIs32:10 FastQC43:00 MultiQC56:40 PycoQCPhiX concentrations for loading a validation…

E8: Nanopore

Jan 16, 2024 57m

Pushing spaghetti through holesChapers:00:00 Intro11:15 Measuring Ions17:00 Quality23:00 Duplex24:30 MinION25:15 PromethION28:20 Methylation29:00 Direct RNA sequencing38:25 Basecalling46:00…

E7: PacBio

Dec 21, 2023 56m

Zipping rounds in zeptolitersChapters:00:00 Intro 07:00 Laser09:00 Zeptoliters13:30 Polymerase speed19:00 Error rate22:00 SMRT Cell25:45 ccs30:00 Fragment size34:30 Megaruptor38:20 Data flow47:00…

E6: Illumina Sequencing Part II

Dec 01, 2023 38m

Glued DNA bridges and rainbow clustersChapters:00:00-Flowcells03:40-DNA glued to glass09:00-Bridge amplification15:50-Cluster density and patterned Flowcells28:30-Illumina SBS…

Frequently Asked Questions

How many episodes does Explain Podcast have?

Explain Podcast has published 28 episodes since June 2023, covering topics in Natural Sciences, Science.

Is Explain Podcast still active?

Explain Podcast is currently active with new episodes monthly. Average episode length is 46m.

How do I contact Explain Podcast for sponsorship or guest appearances?