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S2E13 Silencing Genetic Disease with shRNA | GeneInCell | 2026
shRNA is a gene-silencing tool that uses the cell’s own RNA interference machinery to reduce harmful protein production. In this episode, we explore how short hairpin RNAs are designed to target…
S2E12 Base Editing- Rewriting DNA One Letter at a Time | GeneInCell | 2026
Base editing is changing the future of gene editing by allowing scientists to rewrite DNA one letter at a time. In this episode, we explore how base editors work, why they offer a more precise…
S2E11 siRNAs: Programmable Drugs for Silencing Genetic Disease | GeneInCell
siRNAs are transforming medicine by acting as programmable drugs that selectively silence disease-causing genes. In this episode, we explore how small interfering RNAs work through the RNA…
S2E10 Prime editing: Search and replace for human DNA | GeneInCell | 2026
Prime editing is a next-generation gene editing tool designed to precisely rewrite DNA—like a search-and-replace function for the human genome. In this episode, we break down how prime editing works,…
S2E9 New Approach Methodologies (NAMs) for Replacing Animal Models in Drug Discovery | GeneInCell | 2026
NAMs are changing how new drugs are developed. We discuss organoids, tissue chips, and AI-based tools, along with the growing FDA and NIH push toward more human-relevant methods that can improve…
S2E8 Growing replacement kidneys from stem cells | GeneInCell | 2026
Can we grow new kidneys from stem cells? In this episode, we explore how scientists are using pluripotent stem cells to create kidney organoids that mimic early kidney development. We discuss how…
S2E7 Is Space Travel Safe For You? | GeneInCell | 2026
What really happens to your cells under stress, in space, and during space travel? In this episode, we zoom in on the physiological, cellular, and molecular levels to uncover how zero gravity affects…
S2E6 Growing Beating Human Hearts in a Dish | Heart Organoids | GeneInCell
What does it take to grow a beating human heart in the lab? This episode explores cardiac organoids—self-organizing heart tissues derived from human stem cells that contract, respond to drugs, and…
S2E5 The AI Revolution in Healthcare: 2026 Innovation and Trends | GeneInCell | 2026
In this episode, we explore the AI revolution in healthcare and what 2026 could look like—from smarter diagnostics and personalized treatments to automation that reshapes clinical workflows. We break…
S2E4 Engineering the Next Wave of Innovation with Synthetic Biology | GeneInCell | 2026
Synthetic biology is turning cells into programmable factories, sensors, and therapies. In this episode, we explore how DNA can be engineered like code to build smarter medicines, sustainable…
S2E3 Engineering Blood Vessels for Human Mini Brains | Vascularized Human Brain Organoids | GeneInCell | 2026
How do you give “mini-brains” a bloodstream? This episode explores vascular brain organoids—cerebral organoids engineered with endothelial cells, pericytes, and astrocytes to form BBB-like barriers,…
S2E2 Growing Biological Computers-Brain Organoids From Human Cells | GeneInCell
Brain organoids are self-organizing “mini-brains” grown from human stem cells that recapitulate key aspects of early neural development. They fire neural networks on MEAs, model neurodevelopmental…
S2E1 Building the Human Gut in a Dish From Pluripotent Stem Cells | GeneInCell | 2026
Grow a “mini-gut” from stem cells—fast. This episode maps the journey from pluripotent cells to functional intestinal organoids, covering key signals (Activin A, Wnt3a/R-spondin, EGF), culture…
S1E21 Intestinal 3D Organ Models: Organoids for Drug Testing
Discover how 3D intestinal organoids—mini-gut tissues grown from stem cells—are transforming preclinical drug testing. We break down how these models capture human barrier function, absorption,…
DNA Is Binary Code and Logic | GeneInCell | 2025
DNA as code, cells as computers. We explore how binary models of genomes reveal mutational logic, why evolution mirrors open-source development, and how this lens powers DNA data storage,…
S1E19 DNA Storage: Encoding Digital Data in Nature's Code | GeneInCell
Silicon is hitting its limits—and our data keeps exploding. In this episode, we explore DNA as a radical new archive: a medium with hyper-dense capacity and millennia-scale stability that doesn’t…
S1E2 CRISPR–Cas9 Variants for High-Fidelity Genome Editing
Explore the shift from standard Cas9 nuclease—which makes double-strand breaks—to precision tools like Cas9 nickases (single-strand “nicks”) and dead Cas9 (binding without cutting). We break down how…
S1E17 Human Liver Organoids- From Stem Cells to Therapies
From stem cells to therapies, this episode dives into the world of human liver organoids—how iPSCs are guided into functional “mini-livers,” the bioengineering tricks that mature them, and the…
S1E16 PiggyBac Transposons-A Switchable, High-Capacity Gene Delivery System in Living Cells
How PiggyBac moves DNA in—and out—without scars. We cover transposase mechanics (TTAA-site integration and footprint-free excision), large cargo delivery (tens to ~100 kb), and why it’s popular for…
S1E15 Vascularization, Immune Cells, Organoids and Organ-On-Chip | GeneInCell | 2025
A quick tour of next-gen models that add functional vascularization and immune cells to boost physiological relevance. And strategies (self-assembly, pre-patterning) to build perfusable microvascular…
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GeneInCell has published 34 episodes since August 2025, covering topics in Life Sciences, Science.
GeneInCell is currently active with new episodes weekly. Average episode length is 34m.
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