Invest Like the Best with Patrick O'Shaughnessy

Colossus | Investing & Business Podcasts

English Business Investing Technology

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Episodes 583

Avg. Duration 1h 10m

Activity Highly Active

Apple Rating ★ 4.7 (2,278)

Since Sep 2016

Latest Episode Jun 2026

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Open to Sponsors Features Guests

Publishing Details

Schedule

Weekly

Format

Episodic

Consistency

86%

Hosting

feeds.megaphone.fm

Contact & Outreach

About This Podcast

Conversations with the best investors and business leaders in the world. We explore their ideas, methods, and stories to help you better invest your time and money. Hear stock market and boardroom insights you can't find anywhere else. If you're a professional investor, CEO, entrepreneur, or business strategist, this is for you. Explore all our episodes and learn more at https://www.colossus.com

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Recent Episodes

Alex Sacerdote - How to Invest Through Technology Cycles - [Invest Like the Best, EP.477]

Jun 09, 2026 1h 10m

My guest today is Alex Sacerdote, founder of Whale Rock Capital Management. Whale Rock is a technology focused investment firm that manages more than $17 billion across hedge fund, long only, and…

Dara Khosrowshahi - Uber's Bet on AVs, AI, and Building a Super-App - [Invest Like the Best, EP.476]

Jun 03, 2026 1h 7m

My guest today is Dara Khosrowshahi, the CEO of Uber. Before Uber, Dara ran Expedia for thirteen years. We start with why he took this job in 2017, and a big part of that story is Daniel Ek, who told…

Dan Loeb - Lessons from 30 Years of Investing - [Invest Like the Best, EP.475]

May 28, 2026 1h 3m

My guest today is Dan Loeb, the founder and CEO of Third Point. Dan started Third Point in 1995 with a few million dollars, and today the firm manages over 24 billion across equities, corporate and…

Darren Farber on Iran, China, and the Rise of Neoprimes - [Invest Like the Best, EP.474]

May 26, 2026 46m

My guest today is Darren Farber, and this is his second appearance on the show. Darren is a Managing Partner of Albion River, a defense-focused investment firm and he previously served as a special…

Gavin Baker - Watts and Wafers - [Invest Like the Best, EP.473]

May 20, 2026 1h 16m

My guest today is Gavin Baker, founding partner and CIO of Atreides Management, and this is our sixth conversation. The central theme is watts and wafers, the two physical constraints that in Gavin's…

Krishna Rao - Anthropic's CFO on Compute, Scaling to $30B ARR, and the Returns to Frontier Intelligence - [Invest Like the Best, EP.472]

May 13, 2026 1h 16m

My guest today is Krishna Rao, the CFO of Anthropic. The center of our conversation is how he navigates the decision around procuring and allocating compute, which he describes as the canvas on which…

Brian Chesky - AI Founder Mode - [Invest Like the Best, EP.471]

May 05, 2026 1h 15m

My guest today is Brian Chesky, the co-founder and CEO of Airbnb. Our conversation traces the path from his early training as an industrial designer at RISD through the pandemic moment that forced…

Paul Tudor Jones - Lessons From 50 Years in Markets - [Invest Like the Best, EP.470]

Apr 28, 2026 1h 6m

My guest today is Paul Tudor Jones. Paul is the founder of Tudor Investment Corporation and one of the greatest macro traders of all time, known for calling and profiting from the 1987 crash and…

Dylan Patel - The Infinite Demand for Tokens, Claude Mythos, and Supply Constraints - [Invest Like the Best, EP.469]

Apr 23, 2026 45m

This is my second conversation with Dylan Patel. Dylan is the founder and CEO of SemiAnalysis, where he tracks the semiconductor supply chain and AI infrastructure buildout. This conversation is…

Alex Karnal - The Trillion-Dollar Health Revolution - [Invest Like the Best, EP.468]

Apr 21, 2026 1h 32m

My guest today is Alex Karnal. Alex is the co-founder and managing partner of Braidwell, a life sciences investment firm he built after spending 15 years at Deerfield Management. The frame we use…

Scott Nolan - SpaceX, Founders Fund, and Rebuilding American Uranium Enrichment - [Invest Like the Best, EP.467]

Apr 14, 2026 1h 15m

Scott Nolan spent 12 years at Founders Fund looking for the most important problems that no one else was funding. Then he found a problem so critical, and so ignored, that he couldn't find a company…

Alan Waxman - Private Credit and the Modern Financial System - [Invest Like the Best, EP.466]

Apr 08, 2026 1h 2m

My guest today is Alan Waxman, co-founder and CEO of Sixth Street, a $130B global investment firm. Private credit is one of the most discussed topics in markets right now, and there is a lot to make…

Sergey Levine - Building LLMs for the Physical World - [Invest Like the Best, EP.465]

Mar 31, 2026 1h 6m

My guest today is Sergey Levine, a professor at UC Berkeley and co-founder of Physical Intelligence. The company is building robotic foundation models designed to control any embodied system to do…

Mitchell Green - Lessons from Cold Calling 10,000 Companies - [Invest Like the Best, EP.464]

Mar 24, 2026 54m

My guest today is Mitchell Green. Mitchell Green is the co-founder and managing partner of Lead Edge Capital, a growth equity firm that has spent 15 years building one of the most disciplined…

William Hockey - Building the Operating System for the Dollar and Silicon Valley Heresy - [Invest Like the Best, EP.463]

Mar 17, 2026 1h 10m

William Hockey is the co-founder of Plaid and the founder and CEO of Column, a software company that owns a bank and powers Ramp, Wise, Bilt, Mercury, and others. He funded Column by borrowing…

Shyam Sankar - Celebrating Heretics - [Invest Like the Best, EP.462]

Mar 10, 2026 1h 21m

My guest today is Shyam Sankar, the CTO of Palantir Technologies. In this conversation, we explore the ideas that shape how Shyam thinks about technology, talent, and national power. We discuss the…

John Arnold - China, Energy Markets and Fixing America's Systems - [Invest Like the Best, EP.461]

Mar 04, 2026 1h 15m

My guest today is John Arnold. John is probably the most famous energy trader of all time and certainly the most successful. One of the things John talks about is cultivating the best seat in your…

Dan Sundheim - The Art of Public and Private Market Investing - [Invest Like the Best, EP.460]

Feb 24, 2026 1h 15m

My guest today is Dan Sundheim. Dan is the founder and CIO of D1 Capital Partners. He thinks about markets and businesses constantly, and has built a career entirely around that obsession. He manages…

Josh Kushner - Concentration and Conviction - [Invest Like the Best, EP.459]

Feb 18, 2026 1h 3m

This is my second conversation with Josh Kushner, founder and managing partner of Thrive Capital. I recorded this conversation in October after publishing the Colossus cover story about him and…

Alex Behring and Daniel Schwartz - Inside 3G Capital - [Invest Like the Best, EP.458]

Feb 10, 2026 1h 35m

My guests today are Alex Behring and Daniel Schwartz, Co-Managing Partners of 3G Capital. 3G has built one of the most distinctive firms in investing around a simple idea: there are only a handful of…

Frequently Asked Questions

How many episodes does Invest Like the Best with Patrick O'Shaughnessy have?

Invest Like the Best with Patrick O'Shaughnessy has published 583 episodes since September 2016, covering topics in Business, Investing.

Is Invest Like the Best with Patrick O'Shaughnessy still active?

Invest Like the Best with Patrick O'Shaughnessy is currently highly active with new episodes weekly. Average episode length is 1h 10m.

How do I contact Invest Like the Best with Patrick O'Shaughnessy for sponsorship or guest appearances?

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