M⁴: Medicine, Mystery, Mayhem... and Sometimes Murder
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Ep. 38: It's Your Poison Running Through My Veins
In the 1910s and 1920s, thousands of young women sat at factory benches painting radium onto watch dials, pressing their brushes to their lips to form a fine point with every single stroke. They were…
Ep. 37: Twist and Shout
Some people are born with a blueprint that's slightly off. The structure looks right at first glance, but the details are wrong in ways that matter: joints that stretch too far, a heart that works…
Ep. 36: The Roof, The Roof, The Roof is On Fire
The Clinic That Burned: The Cleveland Clinic Fire of 1929One hundred and twenty-three people went to the doctor. They didn't come home.On May 15, 1929, a fire broke out in the basement of the…
Ep. 35: Wake Up
Sleeping Sickness: The Epidemic That Vanished and the Patients Left BehindIt put millions to sleep. Some of them never woke up. Others woke up wrong.Between 1917 and 1928, a mysterious illness swept…
Ep. 34: I Will Survive
Not every case ends in darkness. This week, Crystal and Andrea bring you something a little different: stories of ordinary people thrust into extraordinary circumstances, and the sheer, stubborn will…
Ep. 33: Get Out, Right Now
In 1955, the United States had 558,000 people living in state psychiatric hospitals. By 2000, that number had dropped to under 55,000. Not because mental illness got better. Not because we found a…
Ep. 32: You Are Not Alone
You're alone. The odds are against you. And then, somehow, you're not alone anymore.Third Man Syndrome is one of the most haunting and hotly debated phenomena in survival psychology — the experience…
Ep. 31: She's So High
They called it non-addictive. They were lying.In this episode, Crystal takes Andrea through the opioid epidemic, one of the deadliest public health crises in American history. From the origins of…
Ep. 30: I Need a Hero?
He was a nurse. He was trusted with the most vulnerable patients in intensive care. And somewhere along the way, the line between saving lives and ending them disappeared entirely.Niels Högel worked…
Ep. 29: Breathe In, Breathe Out
In late 2019, a mysterious respiratory illness began spreading through Wuhan, China. Within months, it had a name — COVID-19 — and within months after that, it had the entire world in its grip.In…
Ep. 28: Paralyzer
You've heard of paralysis. But what if it came and went, triggered by rest, a meal, or exercise, and left no trace by morning? This week, Andrea walks Crystal through Periodic Paralysis, a rare and…
Ep. 27: Mama, Just Killed A Man
A wealthy Utah industrialist is found shot dead in his own warehouse. The scene looks like a robbery. It isn't.What follows is a years-long unraveling of a family held together by money,…
Ep. 26: Can't Sleep, Won't Sleep
Sleep is something we all take for granted until it’s gone.In this episode of Medicine, Mystery, Mayhem & Murder, Andrea and Crystal explore one of the rarest and most terrifying conditions known…
Ep. 25: Down in a Hole
In October 1987, the world held its breath when 18-month-old toddler Jessica McClure, known to millions as Baby Jessica, fell 22 feet down a narrow well in a backyard in Midland, Texas. What followed…
Ep. 24: I am Iron Man
Before ventilators, before modern ICUs, and before vaccines nearly erased one of the most feared diseases in history, there was the iron lung.In this episode of Medicine, Mystery, Mayhem &…
Ep. 23: Doctor, Doctor
In 1999, Dr. Jerri Nielsen was the only physician stationed at the South Pole when she discovered a lump in her breast — after the last plane had already left. With evacuation impossible, she…
Ep. 22: No One Knows What it's Like - Michael Swango Pt 2
In Part Two of our deep dive into Michael Swango, we follow the trail all the way to the end — the arrests, the lies, the international flight, and the staggering body count that may never be fully…
Ep. 21: No One Knows What It’s Like
He wore scrubs. He took an oath. And somehow, he kept getting hired.In Part One of our two-part series, we unravel the early life and chilling rise of one of healthcare’s most unsettling figures:…
Ep. 20: Remember When
Some kids know things they were never taught.They use words too old for their mouths.They recognize places they’ve never been.They speak with a certainty that makes adults stop and stare.In this…
Ep. 19: If You Believe in Miracles
Sometimes you don’t need answers—you just need a breather.This shorter-than-usual episode of Medicine, Mystery, Mayhem & Murder is a palate cleanser for heavy times, focused on miracle survival…
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M⁴: Medicine, Mystery, Mayhem... and Sometimes Murder has published 38 episodes since August 2025, covering topics in True Crime.
M⁴: Medicine, Mystery, Mayhem... and Sometimes Murder is currently highly active with new episodes weekly. Average episode length is 55m.
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