QCast: Data-Driven Dialogue in Drug Development
Quanticate
Publishing Details
About This Podcast
QCast by Quanticate is the podcast for biotech, pharma, and life science leaders looking to deepen their understanding of biometrics and modern drug development. Join co-hosts Tom and Jullia as they explore methodologies, case studies, regulatory shifts, and industry trends shaping the future of clinical research. Where biometric expertise meets data-driven dialogue, QCast delivers practical insights and thought leadership to inform your next breakthrough.
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Recent Episodes
Episode 36: ACR Response Criteria in Rheumatoid Arthritis Trials
In this QCast episode, Jullia and Tom unpack ACR response criteria in rheumatoid arthritis clinical trials and why these endpoints are more operationally demanding than they look on paper. They…
Episode 35: Regulatory Submissions in Clinical Trials
In this QCast episode, Jullia and Tom explore regulatory submissions in clinical trials and why strong submission discipline protects timelines long before any scientific review begins. They discuss…
Episode 34: Therapeutic Areas in Clinical Research
In this QCast episode, Jullia and Tom unpack therapeutic areas in clinical research and why they matter far beyond a clinical label. They discuss how a therapeutic area shapes trial design…
Episode 33: eCRF Design in Clinical Trials
In this QCast episode, Jullia and Tom break down eCRF design in clinical trials and why it has such an outsized impact on data quality, site workload, and downstream analysis. They clarify what an…
Episode 32: Risk-Based Quality Management in CDM
In this QCast episode, Jullia and Tom unpack risk-based quality management (RBQM) in clinical data management and why it’s central to protecting participant safety and the reliability of trial…
Episode 31: Investigator's Brochure (IB)
In this QCast episode, Jullia and Tom break down the Investigator’s Brochure (IB) and why it remains a cornerstone of safe, consistent trial conduct. They explain what an IB is, who relies on it, and…
Episode 30: Adaptive Randomisation in Clinical Trials
In this QCast episode, Jullia and Tom unpack adaptive randomisation in clinical trials and why teams consider it when fixed allocation feels inefficient or ethically uncomfortable. They explain how…
Episode 29: What is Clinical Data Management?
In this QCast episode, Jullia and Tom break down what clinical data management is and why it’s essential to reliable trial decisions. They explain how clinical data management supports patient safety…
Episode 28: Real World Data Analysis in Clinical Trials
In this QCast episode, Jullia and Tom unpack how real world data is analysed to complement clinical trials. They clarify the difference between real world data and real world evidence, explore the…
Episode 27: Machine Learning in the Pharmaceutical Industry
In this QCast episode, Jullia and Tom unpack how machine learning is being applied across the pharmaceutical industry. They discuss what machine learning means in a regulated drug development…
Episode 26: Medical Coding in Clinical Data Management
In this QCast episode, Jullia and Tom explore medical coding in clinical data management, clarifying how clinical narratives are translated into standardised terminology, why consistent coding…
Episode 25: The Proportional Odds Assumption in Clinical Trials
In this QCast episode, Jullia and Tom unpack the proportional odds assumption in ordinal logistic regression, explaining what it means in practice, why it matters for ordinal endpoints in clinical…
Episode 24: Health Economics and Outcomes Research (HEOR)
In this QCast episode, Jullia and Tom explore health economics and outcomes research, explaining how outcomes research looks beyond controlled trials to real world care and how HEOR evidence informs…
Episode 23: Query Management in Clinical Trials
In this QCast episode, Jullia and Tom unpack query management in clinical trials, outlining what queries are, how they move from detection to closure, and how thoughtful design, clear communication,…
Episode 22: Quality Tolerance Limits in Clinical Trials
In this QCast episode, Jullia and Tom explore quality tolerance limits in clinical trials, explaining what they are, how they support risk based quality management, and how to define, monitor and…
Episode 21: The Role of Reconciliation in Clinical Data Management
In this QCast episode, Jullia and Tom unpack data reconciliation in clinical data management — what it is, why it underpins data integrity and safety oversight, and how to plan, run, and document it…
Episode 20: Missing Data in Clinical Trials
In this QCast episode, Jullia and Tom unpack missing data in clinical trials — why it biases effect estimates, how the estimand framework drives prevention and analysis choices, and what good…
Episode 19: Data Validation in Clinical Data Management
In this QCast episode, Jullia and Tom demystify data validation in clinical data management — how a lean, risk-based approach safeguards data integrity and supports confident database lock,…
Episode 18: Real World Evidence in Clinical Trials
In this QCast episode, Jullia and Tom unpack real-world evidence in modern drug development — what distinguishes real-world data from the evidence it enables, and how to apply it alongside randomised…
Episode 17: Dose Expansion Phases in Oncology Trials
In this QCast episode, Jullia and Tom explore the dose expansion phase of phase one oncology trials — the critical bridge between dose finding and proof of concept. They discuss how expansion cohorts…
Frequently Asked Questions
QCast: Data-Driven Dialogue in Drug Development has published 36 episodes since June 2025, covering topics in Life Sciences, Science.
QCast: Data-Driven Dialogue in Drug Development is currently highly active with new episodes weekly. Average episode length is 11m.
