A Dose of Reality with Charles Spence

A Dose of Reality with Charles Spence

Charles Spence

Episodes 69
Avg. Duration 35m
Activity Highly Active
Since Mar 2024
Latest Episode May 2026

Publishing Details

Schedule
Every 2 Weeks
Format
Episodic
Consistency
57%
Hosting
feeds.captivate.fm

About This Podcast

Welcome to “A Dose of Reality”, the podcast where we infuse insight, laughter, and practical wisdom into the world of clinical leadership and career development. Hosted by Charles Spence, each episode offers a deep dive into the challenges and triumphs of clinical leadership, providing listeners with meaningful conversations, career insights, and a dose of inspiration to navigate their professional journeys. Whether you're a director, a C-level executive, or a clinical researcher in oncology bio-techs, this podcast is designed to empower you with the knowledge and tools needed to excel in your field. So, visit our website at www.discera-search.com, and tune in to A Dose of Reality for your prescription of career wisdom, leadership insights, and a healthy dose of laughter.  Subscribe now and join us on the journey to becoming global clinical leaders!

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Recent Episodes

Jens Lindberg, CEO at Medivir, on The Biotech Rollercoaster - Medivir´s Previous Four Months (and Biotech Today in 2026)

May 18, 2026 33m

In this episode, I talked with Jens Lindberg, CEO of Medivir AB, a Swedish biotech developing innovative therapies in liver cancer and rare disease. Jens brings over 30 years of late-stage…

Hubert Truebel, Managing Director at DEBRA Research, on Creating Own Career Opportunities...and a Practical Approach to Longevity

May 04, 2026 28m

In this episode, I talked with Hubert Truebel, Managing Director at DEBRA Research, to discover a career that wasn’t built traditionally—but through creating opportunities where none formally…

Sampreet Ramachandra, Head of Hematology Business Unit at Novartis Germany, on Launching Without a Playbook, Hiring Mistakes, and Leading with Equity

Mar 30, 2026 42m

In this episode, I talked with Sampreet Ramachandra, Head of the Hematology Business Unit at Novartis Germany, about what it really takes to lead high-stakes launches — and what leadership looks like…

Volker Wacheck, SVP at Taiho Oncology in Speaking Up, Asking vs. Accusing and Why Culture is So Important

Mar 09, 2026 29m

In this episode, I talked with Volker Wacheck, SVP & Head of Clinical Development at Taiho Oncology, where he shared how a PI role in Vienna led him into industry, and why the hardest part wasn’t…

Dena Grayson, MD, PhD, SVP Clinical Development & Medical Affairs at Kyverna Therapeutics on Media Training, Communication within Biotech, and Dealing with Fake CVs

Feb 24, 2026 31m

In this episode, I talked with Dr. Dena Grayson, a physician–scientist with over two decades in biotech drug development. At the time of this recording, she was SVP and Head of Clinical Development…

Richard Nkulikiyinka, Chief Medical Officer at Antag Therapeutics, on Career Pivots, Trust and Why Leadership Is Never Linear

Jan 26, 2026 35m

In this episode, I talked with Richard Nkulikiyinka, Chief Medical Officer at Antag Therapeutics, a Copenhagen-based biotech developing GIPR antagonists in the obesity space.Richard’s career began in…

Prof. Dr. med. Markus Kosch, Head of Oncology Europe & Canada at Daiichi Sankyo on Perseverance, Patient-Centricity Beyond Slogans, and Leadership within Oncology

Jan 19, 2026 35m

In this episode, I talked with Prof. Dr. med. Markus Kosch, Head of Oncology Europe and Canada at Daiichi Sankyo Europe, about what it really means to lead with empathy, perseverance, and purpose in…

Myriam Cherif, Founder of Kalyx Medical, on The Future of MSLs, Adapting to AI, and Why Curiosity Keeps You Moving Forward

Jan 05, 2026 33m

In this episode, I talked with Myriam Cherif, former Regional Medical Lead for Oncology & Emerging Markets at GSK and founder of Kalyx Medical—a consultancy focused on Medical Affairs strategy,…

Sven Van den Berghe, CEO of Pantera on Overpromises in Isotope Marketing, Why Culture is the Company, and Discussions in RLT Development

Nov 17, 2025 27m

In this episode, I talked with Sven Van den Berghe, CEO of Pantera, about his 25+ years in nuclear physics, from his early days at the Belgian Nuclear Research Center to stepping into the high-stakes…

Catello Somma, Partner at Seroba on Working in VC, Non-Linear Biotech Careers, and advice for those seeking VC careers

Nov 10, 2025 21m

In this episode, I talked with Catello Somma, Partner at Seroba, to learn about his nonlinear journey from academia and biopharma into venture capital—and the realities behind building funds, backing…

Kevin N. Heller, MD, Chief Medical Officer and Advisor to Funds and VCs, on Culture Shifts, Tough Lessons In Leadership, And The Reality Of Biotech Fundraising

Oct 27, 2025 29m

In this episode, I talked with Dr. Kevin Heller, former biotech CMO and now advisor to VCs and funds, who’s built his career at the intersection of science, leadership, and investment. Kevin started…

Carl Deutsch, CSO at NBE Therapeutics in Non-Linear Careers, Age Bias, and Building Great Teams

Oct 13, 2025 37m

In this episode, I talked with Dr. Carl Deutsch, Chief Scientific Officer at NBE Therapeutics, where he shared about his path from chemistry into pharma and the lessons he’s learned along the way.…

Aleksandra Filipovic, Chief Medical Officer at Gallop Oncology on Perfectionism, Intuition, and the Risk of Building Unsafe Teams

Oct 06, 2025 34m

In this episode, I talked with Dr. Aleksandra Filipovic, CMO at Gallop Oncology, a biotech developing first-in-class galectin-9 antibodies for solid tumors and blood cancers. We talked about how…

Heidi Wang, CEO at OBI Pharma & Chairwoman at OBIGEN Pharma on Losing Her Father to Cancer, Hiring Without Humility, and Building a Culture That Lasts

Sep 22, 2025 27m

In this episode, I talked with Heidi Wang, CEO of OBI Pharma and Chair of OBIGEN, who shares her powerful story, from losing her father to cancer while raising two children, to leading oncology drug…

András Strassz, MD, MBA, CMO at Heidelberg Pharma – Career Crossroads, Recruiting, and Culture Fit Over CVs

Aug 14, 2025 38m

In this episode, I talked with Dr. András Strassz, Chief Medical Officer at Heidelberg Pharma, to hear about his two decades of leadership in oncology drug development—and the often-overlooked…

Steven Katz, MD, CMO and SVP of Translational Science for Shinobi Therapeutics & Professor of Surgery at Brown University - Hiring Without Regret, Team Mismatches, and the Cost of Playing It Safe in Biotech

Aug 04, 2025 36m

In this episode, I talked with Dr. Steven Katz, CMO and SVP of Translational Science for Shinobi Therapeutics, a biotech company pioneering off-the-shelf immune-evasive IPSC-derived cell therapies,…

Christian Mueller, CDO at Immutep on Career Crossroads, Culture Missteps, and the Recruitment Disconnect in Biotech

Jul 29, 2025 35m

In this episode, I talked with Christian Mueller, Chief Development Officer at Immutep. Christian’s path into biotech wasn’t exactly planned—from summarizing VC business plans during his studies to…

Kirsty Crame-van Nierop, Director of Shiaba Consulting, Specialist on Clinical Drug Development, in Broken Hiring Cycles, IND Wins, and Surviving Biotech Burnout

Jul 14, 2025 34m

In this episode, I talked with Kirsty Crame-van Nierop, Director of Shiaba Consulting, Specialist in Clinical Drug Development. Kirsty shares her career journey, including her transition from…

Bernhardt Zeiher, M.D. Member of the board of directors for Entrada Therapeutics, Amylyx Pharmaceuticals, and Abeona Therapeutics on Lessons from Leading a Global Development Organization

Jul 01, 2025 34m

In this episode, I talked with Dr. Bernhardt (Bernie) Zeiher, where he shares key lessons and personal insights from over 25 years in pharmaceutical drug development. Bernie discusses pivotal career…

Ilya Gipp, CMO at GE Healthcare – Imaging’s Role in Oncology, Hiring Lessons, and How Culture Really Works

Jun 16, 2025 38m

In this episode, I talked with Dr. Ilya Gipp, Chief Medical Officer at GE Healthcare, where he shares lessons from a career spent at the intersection of clinical medicine and medtech leadership. He…

Frequently Asked Questions

How many episodes does A Dose of Reality with Charles Spence have?

A Dose of Reality with Charles Spence has published 69 episodes since March 2024, covering topics in Business, Careers.

Is A Dose of Reality with Charles Spence still active?

A Dose of Reality with Charles Spence is currently highly active with new episodes every 2 weeks. Average episode length is 35m.

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