Channel Your Enthusiasm
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A chapter by chapter recap of Burton Rose’s classic, The Clinical Physiology of Acid Base and Electrolyte Disorders, a kidney physiology book for nephrologists, fellows, residents and medical students.
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S1E31 Chapter Twenty One: Respiratory Alkalosis
ReferencesChapter 19, Part 3 August 30, 2023Biff Palmer’s Ted Talk-Why not? Biff Palmer at TEDxSMU 2013Anna mentioned this issue of lactic acidosis in a panic disorder: The Lactic Acid Response to…
S1E30 Chapter Nineteen: Metabolic Acidosis, part 3
ReferencesChapter 19, Part 3 August 30, 2023Joel and Roger mentioned the most common cause seems to be Sjögren’s syndrome for an acquired distal RTA. We mentioned this in an earlier episode and…
S1E29 Chapter Nineteen: Metabolic Acidosis, part 2
ReferencesChapter 19, Part 12Metabolic acidosis June 14, 2023ReferencesChapter 19, Part 2Roger mentioned MELAS syndrome MELAS syndrome: Clinical manifestations, pathogenesis, and treatment…
S1E27 Chapter Eighteen: Metabolic Alkalosis, part 2
ReferencesPart 2, March 1, 2023The alkaline tide phenomenon in studies that measured both the alkaline tide and acid secretion, the bicarbonate accumulation increased in linear fashion with the acid…
S1E28 Chapter Nineteen: Metabolic Acidosis, The Show, part 1
ReferencesChapter 19, Part 1 Metabolic acidosis June 14, 2023American Society of Nephrology | Medical Students - Kidney TREKS this is the program that Josh mentioned at Mount Desert Island! Effects…
S1E26 Chapter Eighteen: Metabolic Alkalosis, part 1
We are a bit slappy at the beginning of the episode since we had just recorded our conversation with the Glaucomfleckens. ReferencesChapter 18 Metabolic alkalosis! Part 1 February 23, 2023It is…
S1E25 Chapter Seventeen: Introduction to Simple and Mixed Acid-Base Disorders
ReferencesI said I used MDCalc but I was mistaken I use MedCalX which is nice but getting dated. We talked about this out of print book that we love: Cohen, J. J., Kassirer, J. P. (1982). Acid-base.…
S1E24 Chapter Sixteen: Edematous States, part 2
ReferencesWe talked about winning the 2022 ASN innovation contest and here’s a link to our promo video…
S1E23 Chapter Sixteen: Edematous States, part 1
ReferencesCapillary Hemodynamics Insights into Salt Handling and Blood Pressure | NEJMAmy mentioned about the 3 phases of the interstitiumAre the precapillary sphincters and metarterioles universal…
S1E22 Chapter Fifteen: Clinical Use of Diuretics, part 2
ReferencesProximal Tubule-Specific Deletion of the NHE3 (Na+/H+ Exchanger 3) in the Kidney Attenuates Ang II (Angiotensin II)-Induced Hypertension in Mice Melanie is in love with this paper that…
S1E21 Chapter Fifteen: Clinical Use of Diuretics, part 1
Outline Chapter 15 — Clinical Use of Diuretics- Among most commonly used drugs- Block NaCl reabsorption at different sites along the nephron- The ability to induce negative balance has made them…
S1E20 Chapter Fourteen: Hypovolemic States, part 2
Outline Chapter 14 — Treatment- Treatment - Both oral and IV treatment can be used for volume replacement - The goal of therapy are to restore normovolemia - And to correct…
S1E19 Chapter Fourteen: Hypovolemic States, part 1
OutlineChapter 14- Hypovolemic States- Etiology - True volume depletion occurs when fluid is lost from from the extracellular fluid at a rate exceeding intake - Can come the GI tract …
S1E18 Chapter Thirteen: Meaning and Application of Urine Chemistries
ReferencesJC mentioned that the diagnostic accuracy of 24 hour urine collection increases with more collections! Metabolic evaluation of patients with recurrent idiopathic calcium nephrolithiasisWe…
S1E16 Chapter Eleven: Regulation of Acid-Base Balance, part 2
ReferencesWe considered the complexity of the machinery to excrete ammonium in the context of research on dietary protein and how high protein intake may increase glomerular pressure and contribute…
S1E15 The 2023 NKF Clinical Meeting Live Recording: Diuretic Draft
The Channelers went where no nephrology podcasters have gone before, recording in front of a live audience at the National Kidney Foundation Clinical Meeting in Austin. We had all eight Channelers…
S1E14 A Very Special Episode: Meet the Glaucomfleckens
S1E13 Chapter Eleven: Regulation of Acid-Base Balance, part 1
ReferencesWe considered the effect of a high protein diet and potential metabolic acidosis on kidney function. This review is of interest by Donald Wesson, a champion for addressing this issue and…
S1E12 Chapter Ten: Acid-Base Physiology
References for Chapter 10We did not mention many references in our discussion today but our listeners may enjoy some of the references below. Effects of pH on Potassium: New Explanations for Old…
S1E11 Chapter Nine: Regulation of Plasma Osmolality
References for Chapter 9One of the few papers that Rose wrote as a single author explores electrolyte free water clearance. This seminal paper explores the issue in greater detail than the book. A…
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Channel Your Enthusiasm has published 30 episodes since January 2021, covering topics in Courses, Education.
Channel Your Enthusiasm is currently highly active with new episodes every 2 months. Average episode length is 1h 33m.
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