No Priors: Artificial Intelligence | Technology | Startups
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Recent Episodes
S1E164 The Rise of the Full-Stack Builder and Hyper-Leveraged Generalist with Microsoft CEO Satya Nadella
What does it mean for a business to truly operate at the AI frontier? In a special crossover episode at Microsoft Build, Sarah Guo and Elad Gil team up with Latent Space host “swyx” to talk with…
S1E163 Building an AI Guardian for Enterprise with Onyx Security CEO Maxim Bar Kogan
We are now closer than ever before to living in a world where AI agents are smart enough to run our power grids and manage water supplies. How do we keep them from going rogue? Sarah Guo sits down…
S1E162 The Story Behind Cerebras’ $63 Billion IPO with Founder and CEO Andrew Feldman
Companies in Silicon Valley from Nvidia to AMD are racing to fuel the AI revolution with postage stamp-sized AI chips. Meanwhile, a chip the size of a dinner plate just fueled a $63 billion IPO for…
S1E161 Pax Silica: Inside the Trump Administration’s Tech Strategy with US Under Secretary of State for Economic Affairs Jacob Helberg
Securing AI dominance requires more than just semiconductors; it demands a complete overhaul of how the West manages everything that goes into them, from rare earth minerals to actuators. Enter: Pax…
S1E160 Amex Global Business Travel: The World’s First AI Take Private with Long Lake CEO Alexander Taubman
The world’s first AI-take-private just proved that AI can revolutionize the real economy. Long Lake Management co-founder and CEO Alexander Taubman joins Elad Gil to discuss his firm’s agreement to…
S1E156 Baseten CEO Tuhin Srivastava on the AI Inference Crunch, Custom Models, and Building the Inference Cloud
Baseten CEO and co-founder Tuhin Srivastava sits down with Sarah Guo and Elad Gil to discuss the rapid growth of AI inference demand, Baseten’s 30x growth, and why inference is becoming the strategic…
S1E158 SAP: Bringing the ‘Operating System’ of a Company into the AI Era with CTO Philipp Herzig
More than fifty years ago, the modern idea of the standard enterprise software was birthed at SAP. Now, after managing companies through technological shifts from the mainframe to mobile, SAP is at…
S1E157 Scaling Global Organizations in the Age of AI with ServiceNow Chairman and CEO Bill McDermott
Few teens are business owners, but by age 16, Bill McDermott had purchased and was running a local deli. Now he runs leading global technology powerhouse ServiceNow, a company that is defining how…
S1E156 The Agentic Economy: How AI Agents Will Transform the Financial System with Circle Co-Founder and CEO Jeremy Allaire
AI agents can already collaborate, but they lack a trustworthy medium in which to store value and execute contracts. Enter Circle’s Arc Blockchain, an economic “operating system” designed for a world…
AI for Atoms: How Periodic Labs is Revolutionizing Materials Engineering with Co-Founder Liam Fedus
What happens when you apply the scaling laws of large language models to the physical work of atoms? Elad Gil sits down with Liam Fedus, co-founder at Periodic Labs, which is pioneering an AI…
S1E154 Andrej Karpathy on Code Agents, AutoResearch, and the Loopy Era of AI
What happens when AI agents can design experiments, collect data, and improve — without a human in the loop? Andrej Karpathy joins Sarah Guo on the state of models, the future of engineering and…
S1E153 From Coder to Manager: Navigating the Shift to Agentic Engineering with Notion Co-Founder Simon Last
Notion isn’t designing AI agents that just use tools. Their agents can autonomously build their own integrations, as well as write the code needed to finish a task. Sarah Guo sits down with Notion…
S1E152 How Capital is Powering the AI Infrastructure Buildout with Magnetar Capital Managing Director Neil Tiwari
By the end of 2026, AI capital expenditure is projected to hit nearly $700 billion. The question isn’t who has the best model, but who has the most creative financing to build out AI infrastructure…
S1E151 From SaaS to AI-First: How Companies Are Reshaping Innovation
In this episode of No Priors, Sarah and Elad dive into the evolving landscape of software, exploring how AI is transforming the traditional SaaS model. They discuss whether SaaS as we know it is…
S1E150 Rivian’s Roadmap to AI Architecture and Autonomy with Founder and CEO RJ Scaringe
Autonomous vehicle technology has moved past human-coded rules and into an era of neural networks and custom computer chips. And to solve the most difficult driving scenarios, electric vehicle…
S1E149 Introducing 4D Creation Open Beta: NPCs, 4D Worlds, and the Future of Gaming with Roblox CEO Dave Baszucki
From “virtual doppelgängers” to “real-time dreaming,” online gaming platform Roblox is using AI technology to build the “Holodeck” envisioned in science fiction decades ago. Sarah Guo and Elad Gil…
S1E148 Why Cryopreservation is No Longer Science Fiction with Until Co-founder and CEO Laura Deming
What if we could pause biological time to wait for a cure for a disease? Thanks to innovations and research in reversible cryopreservation, this possibility is no longer just science fiction. Sarah…
S1E147 No Priors Live: Building Durable Software in the AI Age with MongoDB President & CEO CJ Desai
Why are there only a handful of companies in the world with over $10 billion in pure-play software revenue? CJ Desai believes the reason is that products are replaceable, but platforms are forever.…
S1E146 AI and the Future of Warfare with US Under Secretary of War Emil Michael
Today’s arms race looks a little different from those of the past. Under the Trump administration, the US Department of War (DoW) is deploying generative AI to millions of employees in order to…
S1E145 NVIDIA’s Jensen Huang on Reasoning Models, Robotics, and Refuting the “AI Bubble” Narrative
Even if ChatGPT never existed, the tech giant NVIDIA would still be winning. The end of Moore’s Law—says NVIDIA President, Founder, and CEO Jensen Huang—makes the shift to accelerated computing…
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No Priors: Artificial Intelligence | Technology | Startups has published 165 episodes since February 2023, covering topics in Business, Entrepreneurship.
No Priors: Artificial Intelligence | Technology | Startups is currently highly active with new episodes weekly. Average episode length is 38m.
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