Personal Genomics Zone
Manuel Corpas
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The Future of Genomics is Agentic
A deep dive into agentic AI for bioinformatics: what agents are, how they work, the state of the art in 2026, and why ClawBio's specification layer — SKILL.md — changes how we package and share…
The Bias Amplification Cascade: How Structural Inequities Propagate Through AI
Dr Manuel Corpas presents the HEIM framework and Bias Amplification Cascade at the Molecular Science Research Hub seminar (12 March 2026). The talk covers three dimensions of compounding neglect in…
Agentic Genomics: Living Through the AI Revolution as a Genomicist
Dr Manuel Corpas introduces Agentic Genomics — a framework for how AI agents are transforming bioinformatics. Covers the HEIM equity framework, bias amplification in genomic AI, ClawBio skill…
ClawBio at DoraHacks Demo Day, Imperial College London
Live demo of ClawBio, the first bioinformatics-native AI agent skill library, presented at DoraHacks Demo Day at Imperial College London on 7 March 2026. Covers pharmacogenomics, intelligent routing,…
Peter Steinberger Keynote: Building Open-Source AI Agents — UK AI Agent Hack, Imperial College
Peter Steinberger delivers the keynote at the UK AI Agent Hack at Imperial College London. He discusses building open-source AI agent tooling, setting up a foundation with David Morin to accept…
Vibe Coding: How I Built AI Research Infrastructure Without Engineering Training
How I built a complete AI research infrastructure -- from personal knowledge base to automated pipelines -- without software engineering training. Practical lessons on vibe coding, the six-layer RAG…
How to Learn AI With AI: 7 Actionable Insights for Researchers
Seven actionable insights for researchers on using AI as a learning partner: pair-programming with LLMs, handoff documents, project organisation, autonomous agents, voice interfaces, AI-to-AI…
10 Tips for Becoming a Top 1% AI User
What separates casual AI users from the top 1%? Drawing on lessons from building a personal agentic AI system over six months and insights from Calvin French-Owen (co-founder of Segment, former…
Genetic Diseases in the Era of Precision Medicine
A 71-minute lecture on how genomics is transforming medicine from trial-and-error to targeted, predictive care. Covers the paradigm shift from population averages to personalised treatment, variant…
Building an Agentic AI System: Lessons from Six Weeks in Production
A practical walkthrough of building a personal agentic AI system that runs at production scale. Covering architecture (ChromaDB, Voyage AI, tiered Claude models), a nine-tool Telegram agent called…
Why LLMs Can Hurt Your Academic Writing If You Trust Them Too Much
I spend many hours working with LLMs to help me support my academic writing. This post summarises what I have learned. If you are using LLMs to help write academic papers, grant applications, or…
Superenlightenment: A Personal Manifesto
A personal manifesto on harnessing artificial intelligence as an enabler for a new era of human wisdom and understanding, proposing principles for AI-augmented intellectual work grounded in equity,…
Quantitative Confidence: Navigating Uncertainty in Genomics and Precision Medicine
A deep dive into quantitative confidence in genomics and precision medicine — exploring confidence intervals, p-values, Bayesian methods, calibration, and why honest uncertainty quantification is…
Missing Pieces: Why Genomic Diversity Is the Key to Better Science
Presented at the UK-Indonesia Health Genomics Forum, London, 25 November 2025. When we speak about the future of precision medicine, it is easy to focus on the technology. Yet the real foundation of…
The Precision Medicine Paradox: Why Partial Data Cannot Deliver Global Health
By Dr Manuel Corpas. Precision medicine is built on a contradiction. The field promises individualised care calibrated to each person's biology, yet its foundations rest on data representing a…
Health Data Equity in Latin America in the Age of AI and Genomics
A recap of my presentation to Britcham Brazil, 7 October 2025. This morning I had the privilege of presenting to a distinguished audience at the British Chamber of Commerce and Industry in Brazil.
Biobanking Meets AI
Lectures from Biobanking for Data Science, a module I lead at the University of Westminster for the MSc AI Digital Health course.
My Journey to Advancing Health Equity in Genomics
When I'm asked how I became a scientist, I usually smile, because the truth is, I've been aspiring to be one for over 30 years. My career didn't follow the straight path I once imagined.
Why Diversity Must Be at the Heart of Precision Medicine
Despite breathtaking advances in genomics over the past two decades, we are failing to answer a fundamental question: who benefits from this progress?
Bridging Genomics' Greatest Challenge: The Diversity Gap
Genomics holds the promise to revolutionize healthcare--offering tailored diagnoses, treatments, and prevention strategies. But this vision remains dangerously incomplete without one critical…
Frequently Asked Questions
Personal Genomics Zone has published 24 episodes since January 2025, covering topics in Health & Fitness, Life Sciences.
Personal Genomics Zone is currently dormant with new episodes weekly. Average episode length is 35m.
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