Episodes 45
Avg. Duration 35m
Activity Dormant
Apple Rating 4.5 (582)
Since Sep 2022
Latest Episode Dec 2025

Publishing Details

Schedule
Weekly
Format
Episodic
Consistency
40%
Hosting
www.omnycontent.com

Contact & Outreach

About This Podcast

How terrifying would it be to fight an unknown enemy? One you don’t recognize and didn’t see coming? What if that enemy was coming from within; a disease that even doctors couldn’t identify? Nearly half of all Americans suffer from some chronic illness and many struggle for an accurate diagnosis.

Every other week on Symptomatic, host Lauren Bright Pacheco unravels the medical mystery of a patient’s baffling symptoms and explores how their lives were turned upside down in search of answers. 

From the first signs of trouble, through a swirl of misdirection and failed treatment attempts, to the final relief at a confirmed diagnosis - these are their stories. This is Symptomatic.

We want to hear from you! Tell us what you think of the show or share your own medical mystery by emailing us at [email protected].

Podcasting 2.0 Features

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Recent Episodes

S4E8 Case #33: Phoebe

Dec 23, 2025 41m Transcript

Sarah Marshall knew from only a few months into her fourth daughter Phoebe's life that something was definitely wrong. By the time Phoebe was six, Sarah began to fear for her daughter's life. She…

S4E7 Case #32: Michelle

Dec 16, 2025 38m Transcript

Michelle Shapiro had built a career helping others get healthy when she was hit with a debilitating health crisis. Doctors were unable to identify the cause of her symptoms - no matter how hard…

S4E6 Case #31: Kristen

Dec 09, 2025 43m Transcript

What began as intermittent rashes that popped up years apart turned into excruciating, long term flare ups with no reprieve for Kristen Willard. Unable to sleep, shower, or even put on pants -…

S4E5 Case #30: Rose & Casey

Dec 02, 2025 40m Transcript

Rockstar Casey McPherson and his family were shocked to the core when his daughter Rose was diagnosed with a rare genetic mutation that has no known treatment. Faced with the possibility of losing…

S4E4 Case #29: Cienna

Nov 25, 2025 41m Transcript

For as long as Cienna Ditri can remember, she has had random bouts of “heavy legs”and loss of vision. As she got older - that sensation grew into episodes in which she could not move altogether.…

S4E3 Case #28: Ian

Nov 18, 2025 47m Transcript

Ian Stedman suffered 32 years with full body rashes, debilitating headaches, joint pain and hearing loss without a clear diagnosis. His Mother Barb had gone over 60 years with the same symptoms.…

S4E2 Case #27: Hailey

Nov 11, 2025 42m Transcript

From the moment Hailey got her period, she could tell that something was different about her. Suffering debilitating menstrual cramps and a flow so heavy she would pass out from blood loss…Hailey…

S4E1 Case #26: Nika

Nov 04, 2025 39m Transcript

Nika spent half her life battling a shape-shifting condition that plagued her in various ways for nearly two decades. Fighting chronic pain, fevers, fatigue, and even strokes. In her 30s, after a…

S4 Symptomatic Returns!

Oct 28, 2025 2m Trailer Transcript

New season. New mysteries. Host Lauren Bright Pacheco returns to uncover the hidden truths behind chronic and rare illnesses. These are the stories of symptoms that defy explanation and the people…

A Special Re-Release: Case #17: Every Cure Pt.1 (Dr. David Fajgenbaum)

Sep 09, 2025 42m Bonus Transcript

We’re celebrating Dr. David Fajgenbaum and revisiting one of our most impactful stories. David was just named to the TIME100 Health list and has a powerful new TED Talk—milestones that reflect the…

S3E8 Case #25: Trent (Pt. 2)

Dec 24, 2024 32m Transcript

Just when Trent starts to believe the worst is behind him, an unexpected twist turns his world upside down. He’s forced to confront new challenges that test his resilience and make decisions that…

S3E7 Case #25: Trent (Pt. 1)

Dec 17, 2024 28m Transcript

Trent was a vibrant and successful insurance assessor when his life took an unexpected turn. While working under a car, he sensed something was off. It wasn’t until later that day -- when his legs…

S3 House Calls - Case #16: Lauren

Dec 10, 2024 16m Bonus Transcript

In this next installment of Symptomatic: House Calls, we check in on Lauren from Case #16. Lauren began noticing severe pain that could not be explained away by her professional dancing career. The…

S3E6 Case #24: Sumaira

Dec 03, 2024 43m Transcript

When Sumaira was 24, what seemed like a routine wisdom teeth extraction quickly set off a series of unexpected health issues. Soon after, her vision in her right eye began to fade—a small nuisance…

S3E5 Case #23: Mik

Nov 26, 2024 40m Transcript

Mik’s health challenges began at an early age, with unusual symptoms like recurring staph infections from small cuts—signs that both doctors and her family brushed aside. Later, she experienced rapid…

S3 House Calls - Case #13: Alisha

Nov 19, 2024 16m Bonus Transcript

In this next installment of Symptomatic: House Calls, we catch up with Alisha from Case #13. Spoiler Alert: If you haven’t listened to this episode yet, you might want to do so first HERE. Alisha was…

S3E4 Case #22: Mila

Nov 12, 2024 39m Transcript

In her mid-20s and thriving in a fast-paced communications job, Mila began experiencing symptoms reminiscent of those her mom had managed with diabetes for years. However, as time went on, it became…

S3E3 Case #21: Scott

Nov 05, 2024 38m Transcript

In peak health, Scott's life took a drastic turn when a rare disease nearly claimed it all. Initially misdiagnosed and dismissed, his symptoms escalated into a near-fatal episode, revealing the true…

S3 House Calls - Case #02: Athena

Oct 29, 2024 18m Bonus Transcript

In this bonus episode, we introduce Symptomatic: House Calls. Throughout Season 3, we will reconnect with past guests to get updates on how they’ve been managing their conditions and how their lives…

S3E2 Case #20: Kelly

Oct 22, 2024 36m Transcript

In her early 30s, Kelly was suddenly plagued by a series of inexplicable health issues, from severe heartburn to rapid weight gain, leaving doctors utterly baffled. Misdiagnosed and even subjected to…

Frequently Asked Questions

How many episodes does Symptomatic: A Medical Mystery Podcast have?

Symptomatic: A Medical Mystery Podcast has published 45 episodes since September 2022, covering topics in Documentary, Health & Fitness.

Is Symptomatic: A Medical Mystery Podcast still active?

Symptomatic: A Medical Mystery Podcast is currently dormant with new episodes weekly. Average episode length is 35m.

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