Talking Ketamine Podcast
Talking Ketamine
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Ketamine and Buprenorphine
Ketamine offers rapid relief from severe depression and suicidal ideation, but its effects are often fleeting, creating a “fade” that leaves patients vulnerable. This Stanford study, published in the…
Ketamine Therapeutic Guidelines
Ketamine therapy, a beacon of hope for treatment-resistant depression, has been gaining traction, but its off-label use has raised concerns about standardization and safety. Imagine a powerful…
Ketamine's Hidden Interactions: A Transplant Patient's Tale
This episode dives into a 2026 case report revealing a surprising drug interaction: ketamine, used for pain management, induced the liver to accelerate the breakdown of critical immunosuppressant…
Ketamine with Traditional Antidepressants
Imagine standing in your bathroom, staring down at your current prescription bottles, terrified that your daily SSRI or SNRI might block the effects of your upcoming ketamine treatment. In Episode…
The Emotion Filter
Imagine knowing exactly what someone is feeling, but your brain forces you to second-guess yourself before you can even react. That is the reality of Treatment-Resistant Depression (TRD), which…
Ketamine vs Colorectal Cancer
In Episode 60, we step outside the realms of mental health and anesthesia to explore a groundbreaking 2026 study by Korkmaz and colleagues that asks a shocking question: can ketamine fight cancer…
Ketamine, the Cognitive Enhancer
For decades, neurology has viewed adult brain damage as a relatively permanent state, offering mostly compensatory therapies to help patients adapt to their deficits. But Episode 59 explores a 2026…
Ketamine and Joy
For decades, the clinical focus of treating Major Depressive Disorder has been on alleviating profound sadness. However, traditional monoaminergic antidepressants often fall short of treating…
Ketamine's Brainwave Fingerprint
In Episode 57, we explore a groundbreaking 2026 study out of Hungary by Koncz and colleagues that challenges the foundation of modern psychiatry: do you actually have to “trip” to heal? For years,…
Ketamine's Child
In Episode 56, we explore a fascinating 2026 pharmacokinetics study by Otto and colleagues that completely changes how we view oral ketamine for Treatment-Resistant Depression (TRD). When taken…
Ketamine's Bipolar Balancing Act
Bipolar depression creates an agonizing clinical trap: patients are paralyzed by severe lows, yet traditional antidepressants take weeks to work and carry the terrifying risk of an “affective…
Ketamine Proof of Consciousness
For decades, medicine has sold us the comforting “light switch” theory: under general anesthesia, we simply cease to exist for a few hours. But in Episode 54, we unpack Bruno Tonetto’s terrifying and…
Ketamine as Therapy Multiplier?
In episode 53, we move out of the sterile lab and into the messy real world, examining a large naturalistic study of 224 patients from an Austin clinic. The paper by Kosted and colleagues compares…
The Nine Year Odyssey
For the podcast’s one-year anniversary, we zoom out from single studies to examine a comprehensive masterpiece: the doctoral thesis of Jolien K.E. Veraart, representing nine years of research…
The Nasal Spray Wars
In the world of ketamine therapy, there is a distinct divide: the FDA-approved, insurance-covered “Gold Standard” (Esketamine/Spravato) versus the cheap, off-label generic (Racemic Ketamine). In this…
Ketamine and the Nanoscopic World
For decades, we’ve imagined the synapse as a “chemical soup”—a messy place where one neuron sprays neurotransmitters at another, hoping for a connection. But in this milestone 50th episode, we use…
The Neuroplastic Revolution
For decades, the “Monoamine Dogma” ruled psychiatry: the brain was a chemical soup, depression was a lack of serotonin, and the cure was simply “filling the tank.” But there was always a glitch in…
Ketamine and Diabetes
Patients with diabetes often face a brutal “syndemic”—a tangled web of chronic illness, Relentless nerve pain (neuropathy), and severe depression, all fueled by a common biological enemy: metabolic…
The Patient's Voice
Clinicians measure success in symptom scores and receptor occupancy, but for patients with Treatment-Resistant Depression (TRD), success is defined by something far more personal: the return of…
The Science of Dissociation
For decades, the “trip” caused by ketamine—sensory detachment, time warping, and out-of-body experiences—was seen as a nuisance, a “bug” to be tolerated during anesthesia. But a groundbreaking 2025…
Frequently Asked Questions
Talking Ketamine Podcast has published 65 episodes since November 2024, covering topics in Alternative Health, Health & Fitness.
Talking Ketamine Podcast is currently highly active with new episodes weekly. Average episode length is 13m.
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