The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
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About This Podcast
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.
Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.
This isn’t just self-improvement - it’s human enhancement backed by data.
Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.
Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
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Recent Episodes
World Cup, Sunscreen, Hair Regrowth, Caffeine Chewing Gum, and more... : 1483
Semaglutide Slows Biological Aging A randomized, placebo-controlled study published in Nature Communications found semaglutide slowed biological aging markers by nine percent on…
Brain Fog, Memory Loss, and Alzheimer's Prevention | Dr. Majid Fotuhi : 1482
How to Reverse Cognitive Decline, Grow Your Hippocampus, and Protect Your Brain from Alzheimer's Disease with Nutrition, Exercise, Sleep, and Stress Reduction Your brain is physically shrinking right…
The Foods That Starve Cancer | William Li : 1481
Dr. William Li: Eat to Beat Disease, Extend Longevity, and Hack Your Vascular Health Your body already has a built-in cancer defense system, and the foods you eat can rival prescription drugs at…
I Drink Fat To Look Shredded (Lost 100lbs) : 1480
I used to weigh 300 pounds. I tried every restrictive diet, became a vegan, and trained 90 minutes a day for 18 months with absolute zero results. Everything changed when I drank a cup of yak butter…
Putin Longevity, Pancreatic Cancer Cure, AI Therapy, GLP-1 Breast Cancer... : 1479
Pancreatic Cancer Halted by Virus Injection Researchers injected an engineered virus directly into pancreatic tumors in three patients — the virus replicated inside malignant cells, triggered an…
How to Get Microplastics Out of Your Body | Mara Labs : 1478
Sulforaphane, Detox Pathways, and the Science of Microplastic Removal Microplastics are building up inside your brain, blood, and reproductive tissue, and most detox protocols do nothing to remove…
Peptide Power Without Needles: Smarter Dosing for Longevity | Justin Kirkland : 1477
Needle-Free Peptides, US Manufacturing, BPC-157, Thymosin Alpha-1, GLP-1s, Microneedle Patches, and How to Avoid Contaminated Peptides Peptides are one of the most powerful tools in biohacking and…
Brain Fog Starts in Your Feet (Scientifically Proven) : 1476
I lived with severe brain fog for 15 years. I couldn't focus, my words didn't come easily, and I spent a fortune trying to fix it from the top down...little worked until I realized the problem wasn't…
NASCAR Death, Steroid Olympics, Genetic Age Truth, and Gut Depression... : 1475
Enhanced Games Debut in Las Vegas as the First Openly Drug-Enabled "Biohacker Olympics" The inaugural Enhanced Games took place in Las Vegas with more than 40 elite athletes competing openly while…
Combine Creatine With THIS To Fight The Root Cause of Aging | Andrew Salzman : 1474
How CD38, PARP, and Leaky Gut Are Destroying Your NAD Levels | Dr. Andrew Salzman Your NAD is being drained by two hidden enzymes, your gut may be the starting point of every aging process in your…
The Doctor With Answers To Your Mystery Symptoms | Jessica Peatross : 1473
The Hidden Causes of Brain Fog, Anxiety, and Chronic Illness: Mold, Parasites, Histamine, and Low Cortisol If you're exhausted, inflamed, and can't figure out why, the answer might be hiding in your…
The EXACT Japanese Formula To Live Past 100+ (Simple Steps) : 1471
In this video, I break down the exact biological mechanisms keeping men in Okinawa, Japan, physically dominant and mentally sharp past 100. You don't need million-dollar lab work or intense weight…
This Epic Device Gives You A SUPERBRAIN : 1472
Light Therapy, 40Hz Gamma & Brainwave Entrainment: How BrainTap Resets Sleep, Clears Brain Fog, and Boosts Productivity by 26% Your brain is being starved of the one nutrient it needs most, and…
The Biblical Anti-Aging Fruit That Scientists Are Obsessed With : 1470
The ancient fruit sitting in your grocery store right now outperforms rapamycin, rivals caloric restriction, and triggers a cellular cleanup process that most longevity scientists did not even know…
How To Hack Your Brain's Missing Youth Molecule | Molly Maloof : 1469
Your relationships are reshaping your biology in ways that diet and exercise alone cannot fix, and the science behind it will change how you think about longevity, metabolism, and what it actually…
The 4,000-Year-Old Asian Focus Drug That Is Not A Drug : 1468
Most guys over 40 rely on coffee just to survive the day, completely unaware that they are pushing their brains into a frantic, high-stress state that actually destroys deep focus and accelerates…
Semen Switch, Chewing Gum, Creatine Cheat, Cancer Plants, and Bedtime Risk : 1467
One Creatine Dose Kept Sleep-Deprived Brains 12% Sharper A randomized, double-blind crossover trial kept 29 healthy adults awake for 21 hours straight ... half the time on a single moderate dose of…
Stop Wasting Your Gym Sweat (40 Minutes of This Wins Every Time) | Will Harlow : 1466
If you're over 50 and still doing cardio to stay healthy, you're wasting your time and may actually be making things worse. This episode breaks down the exact movements, supplements, and anti-aging…
The Real Reason She Loses Interest in Sex | John Gray : 1465
The person you love is either raising your hormones or destroying them, and most people have no idea which one is happening to them. John Gray, the author of one of the most beloved relationship…
This Italian Fasting Hack Breaks All The Rules Of Fasting : 1464
If you are constantly bloated, fatigued, and feeling heavy, your gut bacteria have taken over. The standard advice is to just stop eating and do a multi-day water fast. But if your gut is already…
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The Human Upgrade: Biohacking for Longevity & Performance has published 1538 episodes since August 2011, covering topics in Education, Health & Fitness.
The Human Upgrade: Biohacking for Longevity & Performance is currently highly active with new episodes every few days. Average episode length is 58m.
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