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Pancreatic cancer breakthrough came from smart scientists making smart bets—not from politicization of science
The oncology community is still riding the high of the success of daraxonrasib—the first drug to show real promise in treating metastatic pancreatic cancer. The drug doubled overall survival for…
Daraxonrasib’s success in treating pancreatic cancer is a reminder that clinical cancer researchers are heroes
At the American Society of Clinical Oncology annual meeting, the plenary sessions are one of the main events. A handful of clinical research studies are chosen from the thousands that are presented…
The Directors: NCORP PIs discuss the growing complexity of regulatory oversight in clinical cancer research
Getting NCI clinical trials to the community has never been a simple matter. Has it been getting simpler or more difficult? How does research get done at the NCI Community Research Program sites? To…
As FDA’s wheels almost entirely come off, NCI remains sturdy—a cancer moonshot may even be on the horizon
While every agency under HHS, particularly FDA, has seen historic leadership shakeups and massive cuts to personnel and funding over the course of the second Trump administration—NCI has been spared,…
The Cancer History Project debuts first de novo book; meanwhile, FDA snafus continue
In last week’s issue of The Cancer Letter, the cover story featured something special: The first de novo book published by The Cancer History Project. The book, “Backwater to Blockbuster: St. Jude…
Prasad’s “deceit,” plus, ODAC’s tough decision against biomarker-based progression assessment (for now)
In last week’s issue of The Cancer Letter, Paul Goldberg, editor and publisher of The Cancer Letter, and Jacquelyn Cobb, associate editor, each had a big story: Jacquelyn wrote about the April 30…
Reforms pending at USPSTF, plus, FDA rejects promising melanoma drug for the second time
The Cancer Letter’s coverage of HHS-led overhauls of foundational scientific institutions continued last week with two unrelated stories pointing to continued disarray amongst public health…
On the joys of reporting on art as a tool for cancer education
The intersection of art and education is well established, but its application in oncology remains limited. Last week’s issue of The Cancer Letter featured two stories about the role of art in cancer…
The Directors: NCORP PIs discuss the growing complexity of regulatory oversight in clinical cancer research
Getting NCI clinical trials to the community has never been a simple matter. Has it been getting simpler or more difficult? How does research get done at the NCI Community Research Program sites? To…
The Directors: Byrd and Chapman speak about avoiding catastrophism and using bridge funding to keep labs open
In recent months, several directors of cancer centers, appearing on The Directors segment of The Cancer Letter Podcast, mentioned that their institutions are increasingly providing small…
No need for a speculum? A new era of HPV screening
FDA has cleared the first at-home self-collection kit for HPV screening, removing significant obstacles to cervical cancer detection. The kit includes the only FDA-approved HPV assay to individually…
NCI Director Letai wants you to know: Grant money is flowing again post-government shutdown
The Cancer Letter’s most recent cover story featured an in-depth Q&A with Anthony G Letai, director of the National Cancer Institute. In this week’s episode of The Cancer Letter Podcast, Paul…
HHS Secretary Kennedy’s diet advice is heavy on meat and light on scientific consensus
The new 2025-2030 Dietary Guidelines for Americans, or DGA, which inform federal nutrition policies, school meals, and public health education were announced by Health Secretary Robert F. Kennedy Jr.…
With early-onset colorectal cancer on the rise, CRC screening is no longer just your parents’ problem
Vote For The Cancer Letter Podcast at the 2026 Webby Awards!https://vote.webbyawards.com/PublicVoting#/2026/podcasts/shows/science-educationColorectal Cancer Awareness Month is putting a sharper edge…
The Directors: Wistar’s Altieri and ChristianaCare’s Petrelli say partnership of their institutions will go on as the guard changes
Leadership is changing at The Wistar Institute and the Helen F. Graham Cancer Center & Research Institute in the months to come—but the leaders of the two institutions say that this will have…
At a jam-packed NCAB meeting, cancer vaccines and site visits take center stage
Last week’s issue of The Cancer Letter was dominated by one event: the meeting of the National Cancer Advisory Board, the group of experts which advises and assists the NCI director on the activities…
CBER Director Vinay Prasad dared to “say no to drugs”
FDA’s Center for Biologics Evaluation and Research Director Vinay Prasad is set to leave the agency for a second time amid controversy. In a March 6 post on X, FDA Commissioner Marty Makary suggested…
One result, two reactions: GRAIL’s Hall and NCI’s Castle react to negative NHS-Galleri trial outcome
On Feb. 19, GRAIL Inc. announced that its pivotal NHS-Galleri trial failed to meet its primary endpoint of reduction in advanced stage cancers. The media and the market reacted as one would expect:…
Lawsuits brought against Tempus AI raise more questions than answers about DNA privacy in the AI era
Two lawsuits filed within days of each other in the U.S. District Court for the Northern District of Illinois claimed that Tempus AI Inc., an AI-driven precision and genomic testing company, had…
Joni Nelson tells us how her background led her to pursue research that meets the needs of the community
One of Joni D. Nelson’s biggest influences growing up was her maternal grandmother, or Màma, as Nelson would affectionately call her. Despite a third grade education and limited literacy, Màma showed…
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The Cancer Letter has published 92 episodes since February 2025, covering topics in Health & Fitness, Medicine.
The Cancer Letter is currently highly active with new episodes weekly. Average episode length is 31m.
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