The Drug Chat with Dr. Wambui
Dr. Wambui Wamburu
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Recent Episodes
The End of the Lipid Road
We've reached the final episode of our dyslipidemia series! In this episode, we explore several additional lipid-lowering therapies, including fibrates, niacin, omega-3 fatty acids, and Evkeeza…
PCSK9 Inhibitors
Another incredible discovery inside the human body—our built-in recycling system and its surprising role in cholesterol control. What happens when that recycle bin works… or doesn’t? Welcome to the…
Bile Acid Sequestrants/Resins
The human body is remarkably efficient—we’re built with a “waste not” mindset, constantly recycling what we can. Bile acid sequestrants tap directly into that system, turning one of our body’s…
Cholesterol Absorption Inhibitors
Cholesterol doesn't just come from one place.... so let's treat it with more than one approach. In this episode we discuss a unique class that works in your gut to block cholesterol even before it…
Hepatic Cholesterol Synthesis Inhibitors.
Welcome to those that inhibit the "De Novo Synthesis" of cholesterol. We talk about the statins and the new kid on the block Bempedoic acid brand name Nexletol.
Introduction to Dyslipidemias
Not all cholesterol is created equal. In this episode, we breakdown dyslipidemia, review the major lipoproteins, and work through a patient case where the numbers signal rising ASCVD risk -…
Antiplatelets - Protease activated receptor 1 antagonists and a Miscellaneous class.
We are at the end of the road of our anti-platelet pathway exploration!!!! We look at 2 different ways of inhibiting the platelets from forming a clot and the different patient populations that these…
Antiplatelets - Glycoprotein Platelet Inhibitors
In today's episode I give a gigantic high five to our scientists/discoveres! Figuring out yet another way to stop clot formation by working out the puzzle of how platelets work to form a clot. With…
Antiplatelets - Thienopyridines
What a lovely name to pronounce Thienopyridines! Another nugget as to how platelets work to cause clots to form and how this class stops that from happening. Very Sci-Fi how these platelets work.
Antiplatelets - Platelet Aggregation Inhibitors.
In the year 1899 (others say 1897) Asprin was marketed by Bayer Pharmaceuticals. Yep and we still use it today talk of super drug. It's used and indicated in many areas but again tunnel vision in…
Anticoagulants - Direct Thrombin Inhibitors (DTIs)
It's a wrap with the anticoagulants! The DTIs some interesting fun facts especially the one that has to do with Leeches 😊! They came into the market in the 2000s and have been very helpful on this…
Anticoagulants - Factor 10a Inhibitors
Our amazing discoverers/scientists are always at work and in the years of 2000s they gave us this class. The other oral anticoagulants besides Warfarin. Factor 10a inhibitors part of the coagulation…
Anticoagulants- Heparins.
We continue with our oldies but goodies. Heparin was first discovered in 1916!!! Ofcourse we have improved on it since then but they all basically work the same way. Still a huge part of our…
Anticoagulants - Warfarin
Warfarin is over 60 YEARS OLD yet it's the most prescribed oral anticoagulant. Listen up, refresh yourself on this oldie but really a good goodie.
Thrombolytics
A stroke is an emergency! We need to break down that clot, enter the thrombo(clot) lytics(disintegrate) class of drugs.
STROKES
In this episode we discuss strokes. The leading cause of disability, dementia and death globally. We answer questions like what causes a stroke and the types of strokes. This is an important…
Alpha blockade, Alpha agonists, Vasodilators
It's the last few classes of the anti-hypertensive drugs. You may not use this routinely but...... they do lower blood pressure. Very interesting how these work. Or bodies are truly a work of art.
Diuretics
I am sure you have heard them called the "water pill" here is your opportunity to learn or remind thyself of exactly how does this reduce volume (make me pee more). Nope this is not a weight loss…
Calcium Channel Blockers
Hey Podcasters! Calcium Channel Blockers (CCBs). Calcium is found in lots of places in your body but in this episode we stay in the heart and how calcium is used on a normal working day in your…
Angiotensin 2 Receptor Blockers (ARBs)
The second of the RAAS system blockers! Very similar to the ACE Inhibitors with a little twist. "And all the Sartans assembled........."
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The Drug Chat with Dr. Wambui has published 56 episodes since September 2021, covering topics in Health & Fitness, Medicine.
The Drug Chat with Dr. Wambui is currently highly active with new episodes every 2 weeks. Average episode length is 14m.
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